Protein-Lipid Interactions (PDF)
From Membrane Domains to Cellular Networks
(Sprache: Englisch)
In 17 contributions by leading research groups, this first comprehensive handbook in the field covers the interactions between proteins and lipids that make the fabric of biological membranes from every angle. It examines the relevant hermodynamic and...
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In 17 contributions by leading research groups, this first comprehensive handbook in the field covers the interactions between proteins and lipids that make the fabric of biological membranes from every angle. It examines the relevant hermodynamic and structural issues from a basic science perspective, and goes on to discuss biochemical and cell biological processes. The book covers physical principles as well as mechanisms of membrane fusion and fission. Additionally, chapters on bilayer structure and protein-lipid interactions as well as on how proteins shape lipids and vice versa, membrane penetration by toxins, protein sorting, and allosteric regulation of signal transduction across membranes make this a valuable information source for researchers in academia and industry.
Inhaltsverzeichnis zu „Protein-Lipid Interactions (PDF)“
HOW LIPIDS SHAPE PROTEINS Lipid Bilayers, Translocons, and the Shaping of Polypeptide Structure Folding and Stability of Monomeric beta-Barrel Membrane Proteins Principles, Kinetics and Stability of Bacteriorhodopsin Folding Post-Integration Misassembly of Membrane Proteins and Disease HOW PROTEINS SHAPE LIPIDS A Census of Ordered Lipids and Detergents in X-ray Crystal Structures of Integral Membrane Proteins Lipid and Detergent Interactions with Membrane Proteins Derived from Solution NMR MEMBRANE PENETRATION BY TOXINS Lipid Interactions of alpha-Helical Protein Toxins Membrane Recognition and Pore Formation by Bacterial Pore-forming Toxins Mechanism of Membrane Permeation and Pore Formation by Antimicrobial Peptides MECHANISMS OF MEMBRANE FUSION Cell Fusion in Development and Disease Molecular Mechanisms of Intracellular Membrane Fusion Interplay of Proteins and Lipids in Virus Entry by Membrane Fusion CHOLESTEROL, LIPID RAFTS, AND PROTEIN SORTING Protein-Lipid Interactions in the Formation of Raft Microdomains Protein and Lipid Partitioning in Locally Heterogeneous Model Membranes TARGETING OF EXTRINSIC MEMBRANE PROTEIN MODULES TO MEMBRANES AND SIGNAL TRANSDUCTION In vitro and Cellular Membrane Binding Mechanisms of Membrane Targeting Domains Structure and Interactions of C2 Domains at Membrane Surfaces Structural Mechanisms of Allosteric Regulation by Membrane-binding domains
Autoren-Porträt
Lukas Tamm studied Molecular Biology and Biophysics at the University of Basel (Switzerland) and at Cornell University. After obtaining his PhD in Biophysics from the University of Basel in 1982, he moved to Stanford University for postdoctoral work with H. M. McConnell.Returning to Basel, he was appointed as a junior faculty member before joining thefaculty of the University of Virgina in 1990. He currently holds a chair in Molecular Physiology and Biological Physics and served as director of heinterdisciplinary program in biophysics at the University of Virginia from 1999-2003.
Bibliographische Angaben
- 2006, 1. Auflage, 444 Seiten, Englisch
- Herausgegeben: Lukas K. Tamm
- Verlag: Wiley-VCH GmbH
- ISBN-10: 3527606998
- ISBN-13: 9783527606993
- Erscheinungsdatum: 12.05.2006
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