Protein Misfolding, Aggregation and Conformational Diseases / Protein Reviews Bd.4 (PDF)

Name: Protein Misfolding, Aggregation and Conformational Diseases / Protein Reviews Bd.4
Brand: Springer-Verlag GmbH
SKU: 29546165
Price: 213.99 EUR
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Part A: Protein Aggregation and Conformational Diseases (Sprache: Englisch)

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Protein Misfolding, Aggregation, and Conformational Disease, is the first book to discuss significant achievements in protein structure-function relationships in the areas of biochemistry, molecular biology and molecular medicine. This volume summarizes recent achievements in the understanding of the relationships between protein misfolding, aggregation and development of protein deposition disorders. Research indicates that various human disorders, including most neurodegenerative diseases, systemic amyloidoses and many others, arise from the misfolding and aggregation of an underlying protein. Protein Misfolding, Aggregation and Conformational Diseases is an ideal book for biochemists, protein scientists, immunologists, pharmaceutical scientists, and molecular and cellular biologists.

Inhaltsverzeichnis zu „Protein Misfolding, Aggregation and Conformational Diseases / Protein Reviews Bd.4 (PDF)“

Conformational prerequisites of amyloidogenesis.- The generic nature of protein folding and misfolding.- Relative importance of hydrophobicity, net charge and secondary structure propensities in prtein aggregation.- Cytotoxic intermediates in the fibrillation pathway: AB oligomers in Alzheimer's disease as a case study.- Glycosoaminoglycans, proteoglycans and conformational disorders.- Apolipoproteins in different amyloidoses.- Oxidative stress and protein deposition diseases.- Protein aggregation in crowded environment.- Chaperones and conformational disorders.- The aggresome: proteasomes, inclusion bodies and protein aggregation.- Protein aggregation/deposition and ion channel formation and membrane damage.- Visualization of protein deposits in vivo.- Visualization of protein deposits in vitro.- Animcal and cell models of human neurodegenerative disorders.- Index.

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Bibliographische Angaben

2007, 2006, 419 Seiten, Englisch
Herausgegeben: Vladimir N. Uversky, Anthony Fink
Verlag: Springer-Verlag GmbH
ISBN-10: 0387259198
ISBN-13: 9780387259192
Erscheinungsdatum: 24.11.2007

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