Quinone Methides / Wiley Series of Reactive Intermediates (PDF)
(Sprache: Englisch)
Multidisciplinary perspectives and approaches to quinone
methides research
The Wiley Series on Reactive Intermediates in Chemistry and
Biology investigates reactive intermediates from the broadest
possible range of disciplines. The contributions in...
methides research
The Wiley Series on Reactive Intermediates in Chemistry and
Biology investigates reactive intermediates from the broadest
possible range of disciplines. The contributions in...
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Multidisciplinary perspectives and approaches to quinone
methides research
The Wiley Series on Reactive Intermediates in Chemistry and
Biology investigates reactive intermediates from the broadest
possible range of disciplines. The contributions in each volume
offer readers fresh insights into the latest findings, emerging
applications, and ongoing research in the field from a diverse
perspective.
This inaugural volume in the series, Quinone Methides,
represents the first book devoted to this fascinating and useful
intermediate. The authors of this work reflect the many disciplines
and approaches to quinone methides research. The volume therefore
covers a broad range of topics, including theoretical treatments,
generation and detection of intermediates, characterization and
applications in chemistry and biochemistry, and biological
reactivity. Among the chapters are:
* Photochemical generation and characterization of quinone
methides
* Quinone methide stabilization by metal complexation
* Self-immolative dendrimers based on quinone methides
* Characterization of quinone methides by spectral global fitting
and 13C labeling
* Formation and reactions of xenobiotic quinone methides in
biology
* Quinone methides in lignification
With this collection of topics, readers already familiar with
quinone methides have the opportunity to advance their own research
by discovering new inspiration and opportunities in allied areas.
Moreover, the range of topics and perspectives covered make this
volume accessible to readers with a broad range of interests,
including organic and physical chemistry, biochemistry,
biotechnology, and pharmaceutics.
methides research
The Wiley Series on Reactive Intermediates in Chemistry and
Biology investigates reactive intermediates from the broadest
possible range of disciplines. The contributions in each volume
offer readers fresh insights into the latest findings, emerging
applications, and ongoing research in the field from a diverse
perspective.
This inaugural volume in the series, Quinone Methides,
represents the first book devoted to this fascinating and useful
intermediate. The authors of this work reflect the many disciplines
and approaches to quinone methides research. The volume therefore
covers a broad range of topics, including theoretical treatments,
generation and detection of intermediates, characterization and
applications in chemistry and biochemistry, and biological
reactivity. Among the chapters are:
* Photochemical generation and characterization of quinone
methides
* Quinone methide stabilization by metal complexation
* Self-immolative dendrimers based on quinone methides
* Characterization of quinone methides by spectral global fitting
and 13C labeling
* Formation and reactions of xenobiotic quinone methides in
biology
* Quinone methides in lignification
With this collection of topics, readers already familiar with
quinone methides have the opportunity to advance their own research
by discovering new inspiration and opportunities in allied areas.
Moreover, the range of topics and perspectives covered make this
volume accessible to readers with a broad range of interests,
including organic and physical chemistry, biochemistry,
biotechnology, and pharmaceutics.
Inhaltsverzeichnis zu „Quinone Methides / Wiley Series of Reactive Intermediates (PDF)“
Chapter 1: Photochemical Generation and Characterization of Quinone-Methides (Matthew Lukeman). Chapter 2: Modeling Properties and Reactivity of Quinone Methides by DFT calculations (Mauro Freccero and Filippo Doria). Chapter 3: Quinone Methide Stabilization by Metal Complexation (David Milstein and Elena Poverenov). Chapter 4: Intermolecular Applications of o-Quinone Methides (o-QMs) Anionically Generated at Low Temperatures; Kinetic Conditions (Thomas Pettus and Liping Pettus). Chapter 5: Self-Immolative Dendrimers Based on Quinone Methides (Doron Shabat and Rotem Erez). Chapter 6: Ortho-Quinone Methides in Tocopherol Chemistry (Thomas Rosenau and Stefan Böhmdorfer). Chapter 7: Characterizing Quinone Methides by Spectral Global Fitting and 13C Labeling (Edward B. Skibo). Chapter 8: Natural Diterpene and Triterpene Quinone Methides: Structures, Synthesis and Biological Potentials (Qibing Zhou). Chapter 9: Reversible Alkylation of DNA by Quinone Methides (Steven E. Rokita). Chapter 10: Formation and Reactions of Xenobiotic Quinone Methides in Biology (Judy L. Bolton and John A. Thompson). Chapter 11: Quinone Methides and Aza-Quinone Methides as Latent Alkylating Species in the Design of Mechanism-Based Inhibitors of Serine Proteases and ß-Lactamases (Michèle Reboud-Ravaux and Michel Wakselman). Chapter 12: Quinone Methides in Lignification (John Ralph, Paul F. Schatz, Fachuang Lu,Hoon Kim, Takuya Akiyama, and Stephen F. Nelsen).
Autoren-Porträt von S. E. Rokita
STEVEN E. ROKITA, PhD, is Professor in the Department of Chemistry and Biochemistry at the University of Maryland. His research interests lie in sequence and conformation specific reactions of nucleic acids, enzyme-mediated activation of substrates and coenzymes, halogenation and dehalogenation reactions in biology, aromatic substitution and quinone methide generation in bioorganic chemistry, copper- and nickel-mediated reactions in bioinorganic chemistry, and electron transfer in biopolymers. Dr. Rokita has more than eighty publications and twelve patents on file to his credit.
Bibliographische Angaben
- Autor: S. E. Rokita
- 2009, 1. Auflage, 456 Seiten, Englisch
- Verlag: John Wiley & Sons
- ISBN-10: 0470452870
- ISBN-13: 9780470452875
- Erscheinungsdatum: 18.02.2009
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