Solid Support Oligosaccharide Synthesis and Combinatorial Carbohydrate Libraries (PDF)

Preface. Contributors. Solid-Phase Carbohydrate Synthesis: The Early Work (W.-C. Haase & P. Seeberger). The Glycal Assembly Method on Solid Supports: Synthesis of Oligosaccharides and Glycoconjugates (P. Cirillo & S. Danishefsky). The Sulfoxide Glycosylation Method and its Application to Solid-Phase Oligosaccharide Synthesis and the Generation of Combinatorial Libraries (C. Taylor). The Use of O-Glycosyl Trichloroacetimidates for the Polymer-Supported Synthesis of Oligosaccharides (L. Knerr & R. Schmidt). Synthesis of Oligosaccharides on Solid Support Using Thioglycosides and Pentenyl Glycosides (V. Wittmann). Solid-Phase Oligosaccharide Synthesis Using Glycosyl Phosphates (W.-C. Haase, et al.). Stereoselective -Mannosylation on Polymer Support (Y. Ito & H. Ando). Tools for "On-Bead" Monitoring and Analysis in Solid-Phase Oligosaccharide Synthesis (W.-C. Haase, et al.). Polyethyleneglycol -Monomethylether (MPEG)-Supported Solution-Phase Synthesis of Oligosaccharides (J. Krepinsky & S. Douglas). Two-Direction Glycosylations for the Preparation of Libraries of Oligosaccharides (G.-J. Boons & T. Zhu). Carbohydrate Libraries in Solution Using Thioglycosides: From Multistep Synthesis to Programmable, One-Pot Synthesis (E. Simanek & C.-H. Wong). Carbohydrate Libraries by the Random Glycosylation Approach (O. Kanie & O. Hindsgaul). Solid-Phase Synthesis of Biologically Important Glycopeptides (N. Bezay & H. Kunz). Preparation and Screening of Glycopeptide Libraries (P. St. Hilaire, et al.). Index.

PETER H. SEEBERGER is Firmenich Assistant Professor of Chemistry at the Massachusetts Institute of Technology in Cambridge, Massachusetts.

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