The Eukaryotic Replisome: a Guide to Protein Structure and Function / Subcellular Biochemistry Bd.62 (PDF)
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Successful chromosome replication is vital for maintaining the integrity of the genetic material in all forms of cellular life. In humans, there are clear links between chromosome replication defects and genome instability, genetic disease and cancer, making a detailed understanding of the molecular mechanisms of genome duplication vital for future advances in diagnosis and treatment. Inspired by recent exciting breakthroughs in protein structure determination and written by leading experts in the field, The Eukaryotic Replisome: a guide to protein structure and function takes the reader on a guided journey through the intricate molecular machinery of eukaryotic chromosomal DNA replication, from replication origin recognition and the assembly of the pre-replicative complexes in G1 through to the final processing of Okazaki fragments at the end of S-phase. This extensively illustrated book is an invaluable source of information, ideas and inspiration for all those withan interest in chromosome replication, whether from a basic science, translational biology and medical research perspective.
- Autor: Stuart MacNeill
- 2012, 2012, 348 Seiten, Englisch
- Herausgegeben: Stuart MacNeill
- Verlag: Springer-Verlag GmbH
- ISBN-10: 9400745729
- ISBN-13: 9789400745728
- Erscheinungsdatum: 23.08.2012
Abhängig von Bildschirmgröße und eingestellter Schriftgröße kann die Seitenzahl auf Ihrem Lesegerät variieren.
- Dateiformat: PDF
- Größe: 8.76 MB
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