Cyclic-Nucleotide Phosphodiesterases in the Central Nervous System / Wiley series in drug discovery and development (PDF)
From Biology to Drug Discovery
(Sprache: Englisch)
This book reviews advances in understanding phosphodiesterases
within the central nervous system and their therapeutic
applications. A range of expert authors from both academia and
industry describe these, then focus on the areas of greatest
scientific...
within the central nervous system and their therapeutic
applications. A range of expert authors from both academia and
industry describe these, then focus on the areas of greatest
scientific...
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Produktinformationen zu „Cyclic-Nucleotide Phosphodiesterases in the Central Nervous System / Wiley series in drug discovery and development (PDF)“
This book reviews advances in understanding phosphodiesterases
within the central nervous system and their therapeutic
applications. A range of expert authors from both academia and
industry describe these, then focus on the areas of greatest
scientific and medical interest to provide more detailed coverage.
Therapeutic and drug discovery applications are covered for
diseases including Alzheimer's, Parkinson's, schizophrenia,
erectile dysfunction, and spinal cord injuries. There is also a
chapter on drug discovery tools such as in vitro assays and X-ray
structures for medicinal chemistry studies.
within the central nervous system and their therapeutic
applications. A range of expert authors from both academia and
industry describe these, then focus on the areas of greatest
scientific and medical interest to provide more detailed coverage.
Therapeutic and drug discovery applications are covered for
diseases including Alzheimer's, Parkinson's, schizophrenia,
erectile dysfunction, and spinal cord injuries. There is also a
chapter on drug discovery tools such as in vitro assays and X-ray
structures for medicinal chemistry studies.
Autoren-Porträt
NICHOLAS BRANDON works at AstraZeneca within theNeuroscience Innovative Medicines Group. He has spent his career in
drug discovery with a strong interest in developing
phosphodiesterase inhibitors for neuropsychiatric disorders and
understanding the basic mechanisms of phosphodiesterase
function.
ANTHONY WEST is an Associate Professor in the Department
of Neuroscience at Rosalind Franklin University. He has studied PDE
function in the basal ganglia for over fifteen years, focusing on
neurochemical and electrophysiological changes induced by PDE
inhibitors in the healthy brain and in animal models of
Parkinson's disease and Huntington's disease.
Bibliographische Angaben
- 2014, 1. Auflage, 400 Seiten, Englisch
- Herausgegeben: Nicholas J. Brandon, Anthony R. West
- Verlag: John Wiley & Sons
- ISBN-10: 1118836324
- ISBN-13: 9781118836323
- Erscheinungsdatum: 07.03.2014
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- Größe: 14 MB
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Sprache:
Englisch
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