Aminoglycoside Antibiotics / Wiley series in drug discovery and development (PDF)
From Chemical Biology to Drug Discovery
(Sprache: Englisch)
Advances that open new avenues in developing aminoglycoside
antibiotics
During the last twenty years, there have been numerous advances in
the understanding of the chemistry, biochemistry, and recognition
of aminoglycosides. This has led to the...
antibiotics
During the last twenty years, there have been numerous advances in
the understanding of the chemistry, biochemistry, and recognition
of aminoglycosides. This has led to the...
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Advances that open new avenues in developing aminoglycoside
antibiotics
During the last twenty years, there have been numerous advances in
the understanding of the chemistry, biochemistry, and recognition
of aminoglycosides. This has led to the development of novel
antibiotics and opened up new therapeutic targets for intervention.
This is the first book to provide a complete overview of recent
advances in the field and explore their tremendous potential for
drug discovery and rational drug design. With chapters written by
one or more leading experts in their specialty areas, the book
addresses the chemistry, biology, and toxicology of
aminoglycosides.
Aminoglycoside Antibiotics: From Chemical Biology to Drug Discovery
is a great resource for academic and industrial researchers in drug
design and mechanism studies and for researchers studying
antibiotic resistance, antibiotic design and synthesis, and the
discovery of novel pharmaceuticals. It is also a valuable reference
for graduate students in pharmacy, pharmaceutical science,
biophysics, medicinal chemistry, and chemical biology.
antibiotics
During the last twenty years, there have been numerous advances in
the understanding of the chemistry, biochemistry, and recognition
of aminoglycosides. This has led to the development of novel
antibiotics and opened up new therapeutic targets for intervention.
This is the first book to provide a complete overview of recent
advances in the field and explore their tremendous potential for
drug discovery and rational drug design. With chapters written by
one or more leading experts in their specialty areas, the book
addresses the chemistry, biology, and toxicology of
aminoglycosides.
Aminoglycoside Antibiotics: From Chemical Biology to Drug Discovery
is a great resource for academic and industrial researchers in drug
design and mechanism studies and for researchers studying
antibiotic resistance, antibiotic design and synthesis, and the
discovery of novel pharmaceuticals. It is also a valuable reference
for graduate students in pharmacy, pharmaceutical science,
biophysics, medicinal chemistry, and chemical biology.
Inhaltsverzeichnis zu „Aminoglycoside Antibiotics / Wiley series in drug discovery and development (PDF)“
Preface. Contributors. 1. In the Beginning There Was Streptomycin (Julian Davies). 2. The Biochemistry and Genetics of Aminoglycoside Producers (Wolfgang Piepersberg, Khaled M. Aboshanab, Heike Schmidt-Beißner, and Udo F. Wehmeier). 3. Mechanisms of Aminoglycoside Antibiotic Resistance (Tushar Shakya and Gerard D. Wright). 4. Design, Chemical Synthesis, and Antibacterial Activity of Kanamycin and Neomycin Class Aminoglycoside Antibiotics (Jinhua Wang and Cheng-Wei Tom Chang). 5. NMR Structural Studies of Aminoglycoside: RNA Interaction (R. Andrew Marshall and Joseph D. Puglisi). 6. Structural Comparisons Between Prokaryotic and Eukaryotic Ribosomal Decoding A Sites Free and Complexed with Aminoglycosides (Jiro Kondo and Eric Westhof). 7. Binding of Antibiotics to the Aminoacyl-tRNA Site of Bacterial Ribosome (Dale Kling, Christine Chow, and Shahriar Mobashery). 8. Metalloaminoglycosides: Chemistry and Biological Relevance (Nikhil Gokhale, Anjali Patwardhan, and J. A. Cowan). 9. Adverse Effects of Aminoglycoside Therapy (Andra E. Talaska and Jochen Schacht). 10. Targeting HIV-1 RNA with Aminoglycoside Antibiotics and Their Derivatives (Lev Elson-Schwab and Yitzhak Tor). 11. Novel Targets for Aminoglycosides (Dev P. Arya, Nicholas Shaw, and Hongjuan Xi). Index.
Autoren-Porträt von Dev P. Arya
DEV P. ARYA is an Associate Professor of Chemistry and Director of the Laboratory of Medicinal Chemistry at Clemson University. He is a member of the ACS, and currently serves as the Program Chair of the Division of Carbohydrate Chemistry. His research interests lie in the development of nucleic acid targeted drugs.
Bibliographische Angaben
- Autor: Dev P. Arya
- 2007, 1. Auflage, 336 Seiten, Englisch
- Verlag: John Wiley & Sons
- ISBN-10: 0470149663
- ISBN-13: 9780470149669
- Erscheinungsdatum: 30.08.2007
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