An Innovative Approach to Understanding and Treating Cancer: Targeting pH
From Etiopathogenesis to New Therapeutic Avenues
An Innovative Approach to Studying and Treating Cancer: Targeting pH describes one of the few characteristics of cancer that is not shared by normal tissues: the reversal or inversion of the pH gradient when intracellular pH becomes alkaline and...
Leider schon ausverkauft
232.99 €
versandkostenfrei
116 DeutschlandCard Punkte
sammeln
- Lastschrift, Kreditkarte, Paypal, Rechnung
- Kostenlose Rücksendung
- Ratenzahlung möglich
Produktdetails
Produktinformationen zu „An Innovative Approach to Understanding and Treating Cancer: Targeting pH “
Weitere Produktinformationen zu „An Innovative Approach to Understanding and Treating Cancer: Targeting pH “
An Innovative Approach to Studying and Treating Cancer: Targeting pH describes one of the few characteristics of cancer that is not shared by normal tissues: the reversal or inversion of the pH gradient when intracellular pH becomes alkaline and extracellular pH becomes acid. This is now recognized as one of the most selective and differential hallmarks of all cancer cells and tissues, being the opposite of the condition found in normal tissues and a potential target in order to achieve either a stable disease or even regression with no toxicity.
The book discusses topics such as lactic acid and its transport system in the pH paradigm, mechanisms to decrease extra cellular pH and increase intracellular pH, NHE-1 activity in cancer, carbonic anhydrases, vacuolar ATPase proton pump, and the sodium-bicarbonate cotransporter system. Additionally, it discusses complementary pharmacological interventions, cellular acidification and extracellular alkalinization as a new and integral approach to cancer treatment.
Bibliographische Angaben
- Autoren: Tomas Koltai , Stephan J. Reshkin , Salvador Harguindey
- Verlag: Academic Press
- EAN: 9780128190593
Autoren-Porträt von Tomas Koltai, Stephan J. Reshkin, Salvador Harguindey
Tomas Koltai is Board Certified Specialist in Medical Oncology (1985), PhD in Chemistry (1997) and Master's in Sciences in Molecular Oncology, University of Buenos Aires (2011). He has vast experience on cancer treatment at several positions: staff oncologist, Sanatorio Mater Dei, Argentina (1985-1990); Head of Oncology, Central Hospital of the Centro Gallego de Buenos Aires (1990-2000) and Medical Director, at the same institution (2000-2002); Head of the Department of Chemotherapy, National Social Services for Retirees, Argentina (2002-2014); Head of the Department of Oncology, Social Services of the National Food Workers Union, Argentina (2010-2014) and Medical Director at the same institution (2014-2016). He has authored several seminal publications on cancer and created the new "triple-edged cancer treatment?.
Inhaltsverzeichnis zu „An Innovative Approach to Understanding and Treating Cancer: Targeting pH “
PART 1: Metabolism and pH physiopathology of cancer 1. Introduction 2. Cancer metabolism 3. The pH alterations in cancer: causes and consequences 4. Lactic acid and its transport system 5. The sodium hydrogen exchanger 6. The voltage gated sodium channels 7. Carbonic anhydrases 8. Proton pumps 9. The sodium/bicarbonate co-transporter 10. Aquaporins 11. Invadopodia and the migration/invasion process 12. The Sp1 transcription factorPART 1: Therapeutics 13. Pharmacological interventions - Part I 14. Pharmacological interventions - Part II 15. Pharmacological interventions - Part III 16. Pharmacological interventions - Part IV 17. Therapeutics: the scheme 18. Therapeutics: ancillary treatments 19. Preventing metastasis 20. Proton inhibitors in pets' cancer 21. pH-related nanoparticles in cancer treatment 22. Conclusions and future perspectives
Kommentar zu "An Innovative Approach to Understanding and Treating Cancer: Targeting pH"
0 Gebrauchte Artikel zu „An Innovative Approach to Understanding and Treating Cancer: Targeting pH“
| Zustand | Preis | Porto | Zahlung | Verkäufer | Rating |
|---|
Schreiben Sie einen Kommentar zu "An Innovative Approach to Understanding and Treating Cancer: Targeting pH".
Kommentar verfassen