Anaerobiosis and Stemness
An Evolutionary Paradigm for Therapeutic Applications
Anaerobiosis and Stemness: An evolutionary paradigm provides a context for understanding the many complexities and evolutionary features of stem cells and the clinical implications of anaerobiosis stem cells. Combining theoretical and experimental...
Leider schon ausverkauft
135.99 €
versandkostenfrei
Produktdetails
Produktinformationen zu „Anaerobiosis and Stemness “
Weitere Produktinformationen zu „Anaerobiosis and Stemness “
Anaerobiosis and Stemness: An evolutionary paradigm provides a context for understanding the many complexities and evolutionary features of stem cells and the clinical implications of anaerobiosis stem cells. Combining theoretical and experimental knowledge, the authors provide a broad understanding of how the absence or low concentration of oxygen can play an influential role in the maintenance and self-renewal of stem cells and stem cell differentiation. This understanding has clinical implications for the fields of regenerative medicine, cancer biology and transplantation, as well as cell engineering and cell therapy. Anaerobiosis and Stemness is an important resource for stem cell and developmental biologists alike, as well as oncologists, cancer biologists, and researchers using stem cells for regeneration.
Bibliographische Angaben
- Autoren: Zoran Ivanovic , Marija Vlaski-Lafarge
- Verlag: Academic Press
- EAN: 9780128005408
Autoren-Porträt von Zoran Ivanovic, Marija Vlaski-Lafarge
Marija Vlaski Lafarge is staff scientist in R&D Cell Engineering Research Laboratory of French Blood Institute for the regions of Aquitaine and Limousin (Bordeaux, France) and in UMR 5164 CNRS/University of Bordeaux. She obtained her PhD degree at Faculty of Sciences (Cell physiology), University of Belgrade, Serbia. Her scientific activity is devoted to stem cell metabolism and physiology studies. Dr. Vlaski Lafarge presented her work in articles, book chapters and meeting communications. She participated in the grants preparation, reviewed several scientific manuscripts, and governed many student's research projects.
Inhaltsverzeichnis zu „Anaerobiosis and Stemness “
TABLE OF CONTENTS: PREFACE SPECIAL REMARKS 1) What entity could be called a "stem cell?? 2) In situ "normoxia? vs. "hypoxia? Part I: ANAEROBIOSIS AND STEM CELL ENTITY 1) The "hypoxic? stem cell niche 2) Low O2 concentrations and the maintenances of stem cells ex vivo 3) Quiescence/proliferation issue and stem cell niche 4) Metabolic peculiarities of the stem cell entity: energetic metabolism and oxidative status 5) "Hypoxic? signaling, metabolic type, quiescence, self-renewal and differentiation Part II: ANAEROBIC-TO-AEROBIC EUKARYOTE EVOLUTION - A PARADIGM FOR STEM CELL SELF-RENEWAL, COMMITMENT AND DIFFERENTIATION? 1) Evolution of eukaryotes with respect to the appearance and rise of oxygen in the atmosphere: anaerobiosis, facultative aerobiosis and aerobiosis 2) Evolution of mitochondria in eukaryotes and mitochondria "maturing? from stem cells to committed progenitors and mature cells 3) Evolutionary origins of stemness: relationship between self-renewal and ancestral eukaryote biology; conservation of self-renewal principle in parallel with the adaptation to O2 4) Metabolic and genetic features of ancestral eukaryotes vs. metabolism and "master pluripotency genes? of stem cells 5) Some other features concerning the analogy "stem cells - primitive eukaryotes": ABC transporters' anaerobiosis/stemness link 6) Harnessing anaerobic nature of stem cells for the use in regenerative medicine 7) Cancer stem cell case and evolutionary paradigm
Kommentar zu "Anaerobiosis and Stemness"
0 Gebrauchte Artikel zu „Anaerobiosis and Stemness“
Zustand | Preis | Porto | Zahlung | Verkäufer | Rating |
---|
Schreiben Sie einen Kommentar zu "Anaerobiosis and Stemness".
Kommentar verfassen