Aptamers Engineered Nanocarriers for Cancer Therapy
Aptamers Engineered Nanocarriers for Cancer Therapy details the selection technologies, biological characteristics, and clinical uses of aptamer-based nano agents for cancer therapeutics. The book helps facilitate speedy solutions for some of the problems...
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Aptamers Engineered Nanocarriers for Cancer Therapy details the selection technologies, biological characteristics, and clinical uses of aptamer-based nano agents for cancer therapeutics. The book helps facilitate speedy solutions for some of the problems pertaining to the manufacture of nano-aptamers - such as toxicity, thermal stability, cost efficiency, tumor penetration and blood stability. Key chapters cover cell-SELEX technology for aptamer selection, mechanisms of multi-drug resistance of cancer, the relevance of aptamers as anticancer therapies, as well as the broad range of aptamer-functionalized nanostructures available.
This book provides exciting insights into this relatively new approach to cancer therapeutics, and will be of interest to materials scientists, biomedical engineers, molecular biologists, biochemists and clinical scientists, with a focus on cancer therapy.
Bibliographische Angaben
- Herausgegeben:Kesharwani, Prashant
- Verlag: Woodhead Publishing
- EAN: 9780323858816
Autoren-Porträt
Dr. Prashant Kesharwani is presently working as an assistant professor at Department of Pharmaceutics, Jamia Hamdard, New Delhi, India. He is also a receipt of SERB-Ramanujan fellowship (the most prestigious fellowship) from India. Dr. Kesharwani have academic, industrial and research experience at international level (including USA, Malaysia and India). An overarching goal of his current research is the development of nano-engineered drug delivery systems for various diseases. Dr. Kesharwani has more than 300 international publications in well reputed journals and 22 published books (Elsevier). His h-index is 63 and i-10 index is 230 (on April 2023). He is a recipient of several internationally acclaimed awards and research funding from various funding bodies. He has presented many invited talks and oral presentations at prestigious scientific peer-conferences, received international acclaims and awards for research contribution, supervised students/junior researchers and actively participated in outreach and scientific dissemination for the service of wider community.
Inhaltsverzeichnis zu „Aptamers Engineered Nanocarriers for Cancer Therapy “
1. Cell-SELEX technology for aptamer selection2. Biological characteristics of aptamers
3. Mechanisms of multi-drug resistance of cancer
4. Relevance of aptamers as targeting ligands for anticancer therapies
5. Aptamers as smart ligands for nano-carriers cancer targeting
6. Aptamer-functionalized liposomes for targeted cancer therapy
7. Aptamer-functionalized micelles for targeted cancer therapy
8. Aptamer-functionalized nanoparticles for targeted cancer therapy
9. Aptamer-functionalized PLGA nanoparticles for targeted cancer therapy
10. Aptamer-functionalized silica nanoparticles for targeted cancer therapy
11. Aptamer-functionalized gold nanoparticles for targeted cancer therapy
12. Aptamer-functionalized dendrimers for targeted cancer therapy
13. Aptamer-functionalized carbon nanotubes for targeted cancer therapy
14. Aptamer-functionalized quantum dots for targeted cancer therapy
15. Cancer immunotherapy via nucleic acid aptamers
16. Aptamer-based imaging and diagnostics for cancer cells
17. Microdevice-based aptamer sensors
18. Aptamer-based microfluidics for circulating tumor cells
19. Aptamer-based theranostic approaches for treatment of cancer
20. Challenges of aptamers as targeting ligands for anticancer therapies
21. Clinical use and future perspective of aptamers
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