Artemisinin-Based and Other Antimalarials
Detailed Account of Studies by Chinese Scientists Who Discovered and Developed Them
Artemisinin-Based and Other Antimalarials: Detailed Account of Studies by Chinese Scientists Who Discovered and Developed Them provides a historical and scientific background of the discovery and development of artemisinin, artemisinin derivatives,...
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Artemisinin-Based and Other Antimalarials: Detailed Account of Studies by Chinese Scientists Who Discovered and Developed Them provides a historical and scientific background of the discovery and development of artemisinin, artemisinin derivatives, combination drugs and related chemicals. It is a historical document, a scientific treatise, and a fascinating description of innovative research on new drug development that is carried out under extremely difficult conditions. The book also includes detailed experiments, physical-chemical procedures, practical methodologies and clinical trials. It is a valuable reference for students and researchers in the fields of scientific history, medicine, pharmaceutical science, chemistry, pharmacology and toxicology.
Bibliographische Angaben
- Autoren: Guoqiao Li , Ying Li , Zelin Li
- Verlag: Academic Press
- EAN: 9780128131336
Autoren-Porträt von Guoqiao Li, Ying Li, Zelin Li
Professor Li graduated from Guangdong College of Traditional Chinese Medicine in 1955. He has more than 50-years experiences on Qinghaosu (artemisinin). He is the first to prove artemisinin's curative effect on falciparum malaria and severe malaria, and contribute in qinghaosu (artemisinin) research in Project 523. He devised and researched a series of artemisinin-based combinations: dihydroartemisinin-piperaquine phosphate-primaquine combination (CV8) which was registered and produced in Vienam in 1997. It was the first-line treatment drug for malaria and given for free in Vietnam. Dihydroartemisinin-piperaquine phosphate combination, Artemisinin- piperaquine combination both have been registered and produced in China. Dihydroartemisinin-piperaquine combination was included in the 2nd edition of "Malaria treatment Guidelines? by WHO in 2010. He has published over 50 papers on malaria research and artemisinin derivatives.Ying Li received a Ph.D. in Miyagi, Japan, from Tohoku University. Currently a professor in Dalian Maritime University, China, Dr. Li is the Dean of the national key-field innovation team of maritime traffic safety and spatial information technology. For over 20 years, she has contributed to scientific research in the fields of intelligent perception of at-sea target and navigation environment, oil spill detection, waterborne intelligent transportation. Her credentials include: Member, expert committee of the Ministry of Transport, Dr. Li oversaw > 20 national and ministerial projects. Awarded > 30 national patents and been published in > 120 scientific papers. Awarded > 20 provincial and ministerial awards, including second prize for National Technological Invention, special prize for technological invention, Chinese Society of Navigation. Vice chair, "Digital Ocean? special committee, National Committee of International Digital Earth Society of China Vice chair, Navigation Remote Sensing Special Committee of Chinese Society of Navigation.
Inhaltsverzeichnis zu „Artemisinin-Based and Other Antimalarials “
1. Discovery of Artemisinin and History of Research and Discovery of Artemisinin Antimalarials2. Biological Research of Artemisia annua L
3. Chemical Research on Artemisinin
4. Artemisinin Derivatives and Analogues
5. Pharmacological Study on Artemisinin and Its Derivatives
6. Clinical Studies of Artemisinin and its Derivatives
7. Artemether and Lumefantrine Combination
8. Artemisinin and Naphthoquine Phosphate Combination
9. The Combination of Artemisinin Drugs and Pyronaridine
10. Artemisinins and piperaquine phosphate combinations
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