Fluorine in Life Sciences: Pharmaceuticals, Medicinal Diagnostics, and Agrochemicals
Progress in Fluorine Science Series
Fluorine in Life Sciences: Pharmaceuticals, Medicinal Diagnostics and Agrochemicals, volume four in Alain Tressaud's Progress in Fluorine Science series, presents a critical, multidisciplinary overview of the contributions of fluorinated products to solve...
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Fluorine in Life Sciences: Pharmaceuticals, Medicinal Diagnostics and Agrochemicals, volume four in Alain Tressaud's Progress in Fluorine Science series, presents a critical, multidisciplinary overview of the contributions of fluorinated products to solve important global issues in various life science fields, particularly in medicinal chemistry, molecular imaging techniques and agriculture. Edited by recognized experts, this book provides unique coverage of the wide-ranging uses and implications of fluorine and fluorinated compounds. Topics include medicinal monitoring and diagnosis, 19F MRI in medicine and in vivo cell tracking, 18F-labeled radiopharmaceuticals, brain imaging and neurology, risk assessment of reactive metabolites in drug discovery, and more.
Edited by Alain Tressaud, past Chair and founder of the CNRS French Fluorine Network, each book in the collection also includes the work of highly-respected volume editors and contributors from both academia and industry who bring valuable and varied content to this active field.
Bibliographische Angaben
- Herausgegeben:Haufe, Gunter; Leroux, Frederic
- Verlag: Academic Press
- EAN: 9780128127339
Inhaltsverzeichnis zu „Fluorine in Life Sciences: Pharmaceuticals, Medicinal Diagnostics, and Agrochemicals “
1. Emerging Fluorination Methods in Organic Chemistry Relevant for Life Science Application2. Fluorination Patterns in Small Alkyl Groups: Their Impact on Properties Relevant to Drug Discovery
3. Polyfluorinated scaffolds in drug discovery
4. Case Studies of Fluorine in Drug Discovery
5. Recent development in fluorinated antibiotics
6. Fluorosugars as inhibitors of bacterial enzymes
7. Microbial metabolism of fluorinated drugs
8. Influence of fluorination on alcohol hydrogen-bond donating properties
9. Synthesis and Applications of Backbone-Fluorinated Amino Acids
10. 19F-labelled Amino Acids for NMR Structure Analysis of membrane-bound peptides
11. In vivo 19-Fluorine Magnetic Resonance Imaging
12. Fluorine-18 radiolabeling of biologics
13. Serotonin receptor imaging by [18F]-PET
14. Organoboronates: Captors of 18F-fluoride for One-step Radiofluorination of Biomolecules
15. Silicon-Fluoride-Acceptor-based 18F-Radiopharmaceuticals: From basic SiFA chemistry towards its clinical application
16. Bio-relevant fluorine-containing N-heterocycles
17. Recent applications of fluorine in crop protection - New discoveries originating from the unique heptafluoroisopropyl group
18. The Role of Fluorine in the Design of Nicotinic Acetylcholine Receptor (nAChR) Competitive Modulators
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