From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors
From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors, Volume 88, the latest release in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this updated...
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From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors, Volume 88, the latest release in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this updated edition include Targeting muscarinic M1 receptor in neurodegeneration, Photo-switchable allosteric ligands, Computational approaches for the design of mGlu receptor allosteric modulators, Allosteric modulation of GLP-1 receptor in metabolic disorders, Group II mGluR roles in the nervous system and their roles in addiction, RAMPs as allosteric modulators of Class B GPCRs, Structure-based discovery and development of mGlu5 NAMs, and much more.
Bibliographische Angaben
- Herausgegeben:Langmead, Christopher J.
- Verlag: Academic Press
- EAN: 9780128201879
Autoren-Porträt
Christopher Langmead is at Monash University, Vic, Australia
Inhaltsverzeichnis zu „From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors “
The computational modeling of allosteric modulation of metabotropic glutamate receptors Laura Pérez-Benito, Claudia Llinas del Torrent, Leonardo Pardo and Gary Tresadern
Structure-based discovery and development of metabotropic glutamate receptor 5 negative allosteric modulators
Kirstie A. Bennett, John A. Christopher and Benjamin G. Tehan
The function and allosteric control of the human sweet taste receptor
Guy Servant, Terry Kenakin, Lan Zhang, Mark Williams and Nicole Servant
The different aspects of the GABAB receptor allosteric modulation
Julie Kniazeff
RAMPs as allosteric modulators of the calcitonin and calcitonin-like class B G protein-coupled receptors
Augen A. Pioszak and Debbie L. Hay
Strategies and considerations of G-protein-coupled receptor photopharmacology
Alice E. Berizzi and Cyril Goudet
Discovery and pharmacology of the covalent GLP-1 receptor (GLP-1R) allosteric modulator BETP. A novel tool to probe GLP-1R pharmacology
Francis S. Willard, Joseph D. Ho and Kyle W. Sloop
Allosteric modulation of metabotropic glutamate receptors in alcohol use disorder: Insights from preclinical investigations
Kari A. Johnson and David M. Lovinger
Allosteric modulation of muscarinic receptors in alcohol and substance use disorders
Leigh C. Walker and Andrew J. Lawrence
M1 muscarinic acetylcholine receptors: A therapeutic strategy for symptomatic and disease-modifying effects in Alzheimer's disease?
Miriam Scarpa, Sarah Hesse and Sophie J. Bradley
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