Acne
Causes and Practical Management
(Sprache: Englisch)
Learn to accurately diagnose, prevent and treat all three acnes using both traditional and novel approaches to understanding the causes and selecting the most effective treatments.
Acne vulgaris is an extremely common condition. It is troublesome...
Acne vulgaris is an extremely common condition. It is troublesome...
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Klappentext zu „Acne “
Learn to accurately diagnose, prevent and treat all three acnes using both traditional and novel approaches to understanding the causes and selecting the most effective treatments.Acne vulgaris is an extremely common condition. It is troublesome to manage, often persisting into middle age. Exact causes are becoming clear and include several hormonal stimulants, some triggered by the Western diet, and a pathogen ignored for decades. Acnes rosacea and inversa (hidradenitis suppurativa) are discussed from entirely new viewpoints.
Acne: Causes and Practical Management will provide readers at all levels with a practical, well-illustrated approach to fully understanding these disorders; a faster and more cost-effective management regimen and the rationales for their prevention.
In full colour throughout and with over 200 excellent clinical images, key highlights include:
* Full coverage of all acne presentations - acne vulgaris, acne rosacea and acne inversa (hidradenitis suppurativa)
* An integrated view of the causes of the varied and overlapping acnes
* Preventive, novel and curative approaches to treatment
* Medical, surgical, and dietary components of management, fully integrated
* Highly practical focus on prevention, treatment and prophylaxis based on emerging pathogenetic concepts
Brought to you by one of the world's leading authorities on the subject, Acne: Causes and Practical Management will be a valuable re-education for the dermatologist and all those who treat or suffer from these three conditions.
Inhaltsverzeichnis zu „Acne “
Preface ixPractical acne therapy xii
Genetics xii
Diet xii
Hormones xii
Stress xiii
Comedones (plugs in pores) xiii
Blemishes--a brief catalogue xiv
Nodules xv
Scars and sinuses xvi
Support xvii
Introduction xviii
Nomenclature xix
The three acnes and grading xx
Acne vulgaris xx
Acne rosacea xxii
Acne inversa (hidradenitis suppurativa) xxiii
Grading the three acnes xxvi
Acne vulgaris xxvi
Acne rosacea xxvi
Acne inversa (hidradenitis suppurativa) xxvi
1 The three acnes and their impact 1
1.1 Acne vulgaris 1
1.1.1 Terminology 1
1.1.2 The starting point 3
1.2 Acne rosacea 3
1.2.1 The "pimply" part 4
1.2.2 The "redness" part 4
1.2.3 The third part the firm fibrosis 6
1.2.4 Part four--ocular rosacea 7
1.2.5 Putting it all together 7
1.2.6 The inflammatory epiphenomena in acne rosacea 8
1.2.7 The "acne rosacea" versus "rosacea" controversy 12
1.2.8 Summary 12
1.3 Acne inversa (formerly hidradenitis suppurativa) 12
1.3.1 Before the rupture where and why? 15
1.3.2 After the rupture what next? 15
1.3.3 So what invaders are important in acne inversa? 15
1.3.4 What makes this disease behave so much worse than acne vulgaris? 18
1.3.5 So what can one possibly do to settle down all this inflammation? 21
1.3.6 So how do you get rid of all this material? 25
1.3.7 What does the future offer? 25
1.4 The psychology of acne 26
1.4.1 Acne as a stress 26
1.4.2 Acne and self-image 27
1.4.3 Isotretinoin therapy and the psyche 27
1.4.4 The isotretinoin-depression question 28
1.4.5 Isotretinoin in perspective 29
2 The folliculopilosebaceous unit--the normal FPSU
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31
2.1 Anatomy 31
2.2 Genetics 31
2.2.1 Acne vulgaris 31
2.2.2 Acne rosacea 34
2.2.3 Acne inversa/hidradenitis suppurativa (AI/HS) 34
2.2.4 The scottish twins 34
2.3 Epigenetics 35
2.3.1 The farmer's boys 36
2.4 Embryology 36
2.5 Histology 38
2.5.1 Onwards and downwards 38
2.5.2 What is going on inside the FPSU? 40
2.6 Physiology 42
2.6.1 Hair first 42
2.6.2 Oil second 42
2.6.3 Last but definitely not least: the follicle 43
2.6.4 Looking deeper 44
2.7 Biochemistry 44
2.8 Hormones enzymes receptors and the intracrine system 45
2.8.1 The intracrine system 48
2.9 FoxO1 and mTORC1 49
2.9.1 The next step 50
2.9.2 The broad view 51
3 Pathogenetic mechanisms summarized 54
3.1 Acne vulgaris 54
3.2 Acne rosacea 56
3.3 Acne inversa/hidradenitis suppurativa (AI/HS) 57
3.4 Other variants 60
3.4.1 Malassezia folliculitis 60
3.4.2 Eosinophilic pustular folliculitis (ofuji's disease) 62
3.4.3 Dissecting terminal folliculitis 63
3.4.4 Acne keloidalis 63
3.4.5 Epidermal growth factor receptor (EGFR) inhibitor eruption 64
3.4.6 Acné excoriée des jeunes filles 65
4 The acne hormones 67
4.1 The endogenous hormones 67
4.1.1 Androgens and their sources 67
4.1.2 Estrogens and their sources 68
4.1.3 Progesterone and the progesteroids 68
4.1.4 Insulin 69
4.1.5 Growth hormone and insul
2.1 Anatomy 31
2.2 Genetics 31
2.2.1 Acne vulgaris 31
2.2.2 Acne rosacea 34
2.2.3 Acne inversa/hidradenitis suppurativa (AI/HS) 34
2.2.4 The scottish twins 34
2.3 Epigenetics 35
2.3.1 The farmer's boys 36
2.4 Embryology 36
2.5 Histology 38
2.5.1 Onwards and downwards 38
2.5.2 What is going on inside the FPSU? 40
2.6 Physiology 42
2.6.1 Hair first 42
2.6.2 Oil second 42
2.6.3 Last but definitely not least: the follicle 43
2.6.4 Looking deeper 44
2.7 Biochemistry 44
2.8 Hormones enzymes receptors and the intracrine system 45
2.8.1 The intracrine system 48
2.9 FoxO1 and mTORC1 49
2.9.1 The next step 50
2.9.2 The broad view 51
3 Pathogenetic mechanisms summarized 54
3.1 Acne vulgaris 54
3.2 Acne rosacea 56
3.3 Acne inversa/hidradenitis suppurativa (AI/HS) 57
3.4 Other variants 60
3.4.1 Malassezia folliculitis 60
3.4.2 Eosinophilic pustular folliculitis (ofuji's disease) 62
3.4.3 Dissecting terminal folliculitis 63
3.4.4 Acne keloidalis 63
3.4.5 Epidermal growth factor receptor (EGFR) inhibitor eruption 64
3.4.6 Acné excoriée des jeunes filles 65
4 The acne hormones 67
4.1 The endogenous hormones 67
4.1.1 Androgens and their sources 67
4.1.2 Estrogens and their sources 68
4.1.3 Progesterone and the progesteroids 68
4.1.4 Insulin 69
4.1.5 Growth hormone and insul
... weniger
Bibliographische Angaben
- Autor: F. William Danby
- 2015, 1. Auflage, 256 Seiten, Maße: 20,8 x 26 cm, Gebunden, Englisch
- Verlag: Wiley & Sons
- ISBN-10: 1118232771
- ISBN-13: 9781118232774
- Erscheinungsdatum: 06.02.2015
Sprache:
Englisch
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