Antigen Antibody Interactions

1. Introduction.- 1. Organization of the Immune System.- 2. Antibody Structure.- 3. The Theory of Clonal Selection.- 2. Hinge and Valence Effects on Antibody Binding Properties.- 1. General Considerations.- 2. The Two-Particle Probability Density Function.- 3. The Crothers-Metzger Model.- 4. Analysis of Experiments.- 5. Immunological Implications.- 3. Combining site heterogeneity. The free energy distribution function.- 1. Statement of the Problem.- 2. Inversion of the Binding Curve.- 3. Intramolecular Reactions.- 4. Immunological Implications.- 4. Combining Site Heterogeneity. Immunodiffusion.- 1. General Remarks.- 2. A Simple Diffusion-Reaction Model for Plaque Formation.- 3. The Solution.- 4. Applications.- 5. The Theory of Plaque Growth Kinetics For A Lymphocyte SOURCE.- 1. Introduction.- 2. A Diffusion-Reaction Model.- 3. Solutions Under Limiting Conditions.- 4. Models Allowing Reversible Reactions.- 5. A Diffusion-Transport-Reaction Model. Electrophoresis.- 6. Predictions of the Theory.- 6. Plaque Inhibition: Growth In The Presence Of Competitive Interactions.- 1. Introduction.- 2. IgG Plaque Inhibition.- 3. Predictions.- 7. Applications Of Plaque Growth Theory And Immunological Implications.- 1. The IgM Response.- 2. The IgG Response.- 3. Summary of Conclusions.- 8. Dynamical Phenomena on Lymphocyte Membranes.- 1. Background and Definitions.- 2. The Dynamics of Antigen-Antibody Aggregation in Three Dimensions.- 3. Critical Coalescence on Lymphocyte Membranes.- 4. Immunological Implications of the Model.- 5. Future Problems.