Asymmetric Synthesis with Chemical and Biological Methods

STOICHIOMETRIC ASYMMETRIC SYNTHESISDevelopment of Novel Enantioselective Synthetic MethodsAsymmetric Synthesis of Natural Products Employing the SAMP/RAMP-Hydrazone MethodologyAsymmetric Synthesis Based on Sulfonimidoyl-Substituted Allyltitanium ComplexesThe "Daniphos" Ligands: Synthesis and Catalytic ApplicationsNew Chiral Ligands Based on Substituted HeterometallocenesCATALYTIC ASYMMETRIC SYNTHESIS WITH CHEMICAL METHODSSulfoximines as Ligands in Asymmetric Metal CatalysisCatalyzed Asymmetric Aryl Transfer ReactionsSubstituted [2.2]-Paracyclophane Derivatives as Efficient Ligands for Asymmetric 1,2- and 1,4-Addition ReactionsPalladium-Catalyzed Allylic Alkylation of Sulfur and Oxygen Nucleophiles - Asymmetric Synthesis, Kinetic Resolution and Dynamic Kinetic ResolutionThe QUINAPHOS Ligand Family and its Application in Asymmetric SynthesisImmobilization of Transition Metal Complexes and their Application to Enantioselective CatalysisCATALYTIC ASYMMETRIC SYNTHESIS WITH BIOLOGICAL METHODSDirected Evolution to Increase the Substrate Range of Benzoylformate Decarboxylase from Pseudomonas PutidaC-C Bonding Microbial Enzymes: Thiamine Diphosphate-Dependent Enzymes and Class I AldolasesEnzymes for Carboligation - 2-Ketoacid Decarboxylases and Hydroxynitrile LyasesPreparative Syntheses of Chiral Alcohols using (R)-specific Alcohol Dehydrogenases from Lactobacillus strainsBiocatalytic C-C Bond Formation in Asymmetric SynthesisExploring and Broadening the Biocatalytic Properties of Recombinant Sucrose Synthase 1 for the Synthesis of Sucrose AnaloguesFlexible Asymmetric Redox Reactions and C-C Bond Formation by Bioorganic Synthetic StrategiesREACTION TECHNOLOGY IN ASYMMETRIC SYNTHESISReaction Engineering in Asymmetric SynthesisBiocatalyzed Asymmetric Syntheses Using Gel-Stabilized Aqueous-Organic Two-Phase Systems

Dieter Enders completed his PhD at the Justus-Liebig-Universität Giessen under the supervision of D. Seebach. After postdoctoral studies at Harvard University with E. J. Corey, he returned to Giessen and completed his habilitation. He became associate professor at the Universität Bonn in 1980, and moved to his present position as Professor of Organic Chemistry at the RWTH Aachen in 1985. He has received many awards (Leibniz-Award of the DFG, Emil Fischer Award of the GDCh, Yamada Award, Japan) for his research, which focuses on the asymmetric synthesis of biologically active compounds and the development of new synthetic methods.

Karl-Erich Jaeger was born in Dortmund and studied biology and chemistry at the Ruhr-University Bochum, where he received his PhD. After postdoctoral studies with Robert E.W. Hancock at the Department of Microbiology of the University of British Columbia, he received his habilitation in Bochum in 1995. Karl-Erich Jaeger is currently Professor at the Heinrich-Heine University of Düsseldorf and Director of the Institute of Molecular Enzyme Technology at the Research Centre Jülich. His research interests are enantionselective biocatalyis and directed evolution of enzymes.

Reasonable contribution to the literature and indeed is a fantastic testimony to SFB 280 and its many talent participants. ( Journal of the American Chemical Society , July 9, 2008)