Bioinorganic Chemistry: Inorganic Elements in the Chemistry of Life
An Introduction and Guide
(Sprache: Englisch)
Bioinorganic Chemistry provides a clear and concise introduction to the role of inorganic elements in biology. Starting with the function and occurrence of inorganic elements in living organisms, the book moves on to address the applications of these...
Leider schon ausverkauft
versandkostenfrei
Buch (Kartoniert)
57.00 €
28 DeutschlandCard Punkte
sammeln
- Lastschrift, Kreditkarte, Paypal, Rechnung
- Kostenlose Rücksendung
- Ratenzahlung möglich
Produktdetails
Produktinformationen zu „Bioinorganic Chemistry: Inorganic Elements in the Chemistry of Life “
Bioinorganic Chemistry provides a clear and concise introduction to the role of inorganic elements in biology. Starting with the function and occurrence of inorganic elements in living organisms, the book moves on to address the applications of these biominerals, inorganic electrolytes and inorganic compounds in fields such as chemotherapy and radiodiagnostics. Topics covered include:
- cobalt in vitamin and coenzyme B12
- the role of magnesium and manganese in photosynthesis
- uptake, transport, and storage of essential elements
- catalysis through hemoproteins
- iron-sulfur and other non-heme iron proteins
- nickel-containing enzymes
- copper-containing proteins
- biological functions of molybdenum, tungsten, vanadium and chromium
- structural and gene-regulatory functions of zinc and its role in the enzymatic catalysis of
- function and transport of alkali and alkaline earth metal cations
- catalysis and regulation of bioenergetic processes by the alkaline earth metal ions Mg2+ and Ca2+
- biomineralization
- biological functions of the non-metallic inorganic elements
- bioinorganic chemistry of toxic metals
- biochemical behaviour of inorganic radionucleides
- chemotherapy whith compounds of non-essential elements
This second edition has been fully revised and updated to take account of the latest findings in the field. New topics have been added, including neurotransmitter gases such as NO; life under extreme conditions; materials aspect of bioinorganic chemistry; elemental cycles; bioorganometallic chemistry; imaging with bioinorganic substances; and therapeutic advances.
Bioinorganic Chemistry is essential reading for advanced students of chemistry, biochemistry, biology, medicine and environmental science. of alkali and alkaline earth metal cations
- catalysis and regulation of bioenergetic processes by the alkaline earth metal ions Mg2+ and Ca2+
- biomineralization
- biological functions of the non-metallic inorganic elements
- bioinorganic chemistry of toxic metals
- biochemical behaviour of inorganic radionucleides
- chemotherapy whith compounds of non-essential elements
This second edition has been fully revised and updated to take account of the latest findings in the field. New topics have been added, including neurotransmitter gases such as NO; life under extreme conditions; materials aspect of bioinorganic chemistry; elemental cycles; bioorganometallic chemistry; imaging with bioinorganic substances; and therapeutic advances.
Bioinorganic Chemistry is essential reading for advanced students of chemistry, biochemistry, biology, medicine and enviro
- cobalt in vitamin and coenzyme B12
- the role of magnesium and manganese in photosynthesis
- uptake, transport, and storage of essential elements
- catalysis through hemoproteins
- iron-sulfur and other non-heme iron proteins
- nickel-containing enzymes
- copper-containing proteins
- biological functions of molybdenum, tungsten, vanadium and chromium
- structural and gene-regulatory functions of zinc and its role in the enzymatic catalysis of
- function and transport of alkali and alkaline earth metal cations
- catalysis and regulation of bioenergetic processes by the alkaline earth metal ions Mg2+ and Ca2+
- biomineralization
- biological functions of the non-metallic inorganic elements
- bioinorganic chemistry of toxic metals
- biochemical behaviour of inorganic radionucleides
- chemotherapy whith compounds of non-essential elements
This second edition has been fully revised and updated to take account of the latest findings in the field. New topics have been added, including neurotransmitter gases such as NO; life under extreme conditions; materials aspect of bioinorganic chemistry; elemental cycles; bioorganometallic chemistry; imaging with bioinorganic substances; and therapeutic advances.
Bioinorganic Chemistry is essential reading for advanced students of chemistry, biochemistry, biology, medicine and environmental science. of alkali and alkaline earth metal cations
- catalysis and regulation of bioenergetic processes by the alkaline earth metal ions Mg2+ and Ca2+
- biomineralization
- biological functions of the non-metallic inorganic elements
- bioinorganic chemistry of toxic metals
- biochemical behaviour of inorganic radionucleides
- chemotherapy whith compounds of non-essential elements
This second edition has been fully revised and updated to take account of the latest findings in the field. New topics have been added, including neurotransmitter gases such as NO; life under extreme conditions; materials aspect of bioinorganic chemistry; elemental cycles; bioorganometallic chemistry; imaging with bioinorganic substances; and therapeutic advances.
Bioinorganic Chemistry is essential reading for advanced students of chemistry, biochemistry, biology, medicine and enviro
Klappentext zu „Bioinorganic Chemistry: Inorganic Elements in the Chemistry of Life “
The field of Bioinorganic Chemistry has grown significantly in recent years; now one of the major sub-disciplines of Inorganic Chemistry, it has also pervaded other areas of the life sciences due to its highly interdisciplinary nature.Bioinorganic Chemistry: Inorganic Elements in the Chemistry of Life, Second Edition provides a detailed introduction to the role of inorganic elements in biology, taking a systematic element-by-element approach to the topic. The second edition of this classic text has been fully revised and updated to include new structure information, emerging developments in the field, and an increased focus on medical applications of inorganic compounds. New topics have been added including materials aspects of bioinorganic chemistry, elemental cycles, bioorganometallic chemistry, medical imaging and therapeutic advances.
Topics covered include:
* Metals at the center of photosynthesis
* Uptake, transport, and storage of essential elements
* Catalysis through hemoproteins
* Biological functions of molybdenum, tungsten, vanadium and chromium
* Function and transport of alkaline and alkaline earth metal cations
* Biomineralization
* Biological functions of the non-metallic inorganic elements
* Bioinorganic chemistry of toxic metals
* Biochemical behavior of radionuclides and medical imaging using inorganic compounds
* Chemotherapy involving non-essential elements
This full color text provides a concise and comprehensive review of bioinorganic chemistry for advanced students of chemistry, biochemistry, biology, medicine and environmental science.
Inhaltsverzeichnis zu „Bioinorganic Chemistry: Inorganic Elements in the Chemistry of Life “
Preface to the Second Edition xiPreface to the First Edition xiii
1 Historical Background, Current Relevance and Perspectives 1
References 6
2 Some General Principles 7
2.1 Occurrence and Availability of Inorganic Elements in Organisms 7
Insertion: The Chelate Effect 14
Insertion: "Hard" and "Soft" Coordination Centers 14
2.2 Biological Functions of Inorganic Elements 14
2.3 Biological Ligands for Metal Ions 16
2.3.1 Coordination by Proteins: Comments on Enzymatic Catalysis 17
Insertion: The "Entatic State" in Enzymatic Catalysis 20
2.3.2 Tetrapyrrole Ligands and Other Macrocycles 22
Insertion: Electron Spin States in Transition Metal Ions 28
2.3.3 Nucleobases, Nucleotides and Nucleic Acids (RNA, DNA) as Ligands 31
Insertion: Secondary Bonding 32
2.4 Relevance of Model Compounds 34
References 34
3 Cobalamins, Including Vitamin and Coenzyme B12 37
3.1 History and Structural Characterization 37
Insertion: Bioorganometallics I [1] 38
3.2 General Reactions of Alkylcobalamins 41
3.2.1 One-electron Reduction and Oxidation 41
3.2.2 Co-C Bond Cleavage 42
Insertion: Electron Paramagnetic Resonance I 43
3.3 Enzyme Functions of Cobalamins 45
3.3.1 Adenosylcobalamin (AdoCbl)-dependent Isomerases 45
Insertion: Organic Redox Coenzymes 48
3.3.2 Alkylation Reactions of Methylcobalamin (MeCbl)-dependent Alkyl Transferases 51
3.4 Model Systems and the Enzymatic Activation of the Co-C Bond 52
References 53
4 Metals at the Center of Photosynthesis: Magnesium and Manganese 57
4.1 Volume and Efficiency of Photosynthesis 57
4.2 Primary Processes in Photosynthesis 59
4.2.1 Light Absorption (Energy Acquisition) 59
4.2.2 Exciton Transport (Directed Energy Transfer)
... mehr
59
4.2.3 Charge Separation and Electron Transport 62
Insertion: Structure Determination by X-ray Diffraction 62
4.3 Manganese-catalyzed Oxidation of Water to O2 68
Insertion: Spin-Spin Coupling 73
References 75
5 The Dioxygen Molecule, O2: Uptake, Transport and Storage of an Inorganic Natural Product 77
5.1 Molecular and Chemical Properties of Dioxygen, O2 77
5.2 Oxygen Transport and Storage through Hemoglobin and Myoglobin 82
5.3 Alternative Oxygen Transport in Some Lower Animals: Hemerythrin and Hemocyanin 92
5.3.1 Magnetism 92
5.3.2 Light Absorption 93
5.3.3 Vibrational Spectroscopy 93
Insertion: Resonance Raman Spectroscopy 93
5.3.4 M¨ossbauer Spectroscopy 94
Insertion: M¨ossbauer Spectroscopy 94
5.3.5 Structure 95
5.4 Conclusion 96
References 96
6 Catalysis through Hemoproteins: Electron Transfer, Oxygen Activation and Metabolism of Inorganic Intermediates 99
6.1 Cytochromes 101
6.2 Cytochrome P-450: Oxygen Transfer from O2 to Nonactivated Substrates 103
6.3 Peroxidases: Detoxification and Utilization of Doubly Reduced Dioxygen 108
6.4 Controlling the Reaction Mechanism of the Oxyheme Group: Generation and Function of Organic Free Radicals 110
6.5 Hemoproteins in the Catalytic Transformation of Partially Reduced Nitrogen and Sulfur Compounds 112
Insertion: Gasotransmitters 113
References 114
7 Iron-Sulfur and Other Non-heme Iron Proteins 117
7.1 Biological Relevance of the Element Combination Iron-Sulfur 117
Insertion: Extremophiles and Bioinorganic Chemistry 118
&nb
4.2.3 Charge Separation and Electron Transport 62
Insertion: Structure Determination by X-ray Diffraction 62
4.3 Manganese-catalyzed Oxidation of Water to O2 68
Insertion: Spin-Spin Coupling 73
References 75
5 The Dioxygen Molecule, O2: Uptake, Transport and Storage of an Inorganic Natural Product 77
5.1 Molecular and Chemical Properties of Dioxygen, O2 77
5.2 Oxygen Transport and Storage through Hemoglobin and Myoglobin 82
5.3 Alternative Oxygen Transport in Some Lower Animals: Hemerythrin and Hemocyanin 92
5.3.1 Magnetism 92
5.3.2 Light Absorption 93
5.3.3 Vibrational Spectroscopy 93
Insertion: Resonance Raman Spectroscopy 93
5.3.4 M¨ossbauer Spectroscopy 94
Insertion: M¨ossbauer Spectroscopy 94
5.3.5 Structure 95
5.4 Conclusion 96
References 96
6 Catalysis through Hemoproteins: Electron Transfer, Oxygen Activation and Metabolism of Inorganic Intermediates 99
6.1 Cytochromes 101
6.2 Cytochrome P-450: Oxygen Transfer from O2 to Nonactivated Substrates 103
6.3 Peroxidases: Detoxification and Utilization of Doubly Reduced Dioxygen 108
6.4 Controlling the Reaction Mechanism of the Oxyheme Group: Generation and Function of Organic Free Radicals 110
6.5 Hemoproteins in the Catalytic Transformation of Partially Reduced Nitrogen and Sulfur Compounds 112
Insertion: Gasotransmitters 113
References 114
7 Iron-Sulfur and Other Non-heme Iron Proteins 117
7.1 Biological Relevance of the Element Combination Iron-Sulfur 117
Insertion: Extremophiles and Bioinorganic Chemistry 118
&nb
... weniger
Bibliographische Angaben
- Autoren: Wolfgang Kaim , Brigitte Schwederski , Axel Klein
- 2013, 2. Aufl., 426 Seiten, Maße: 18,7 x 24,6 cm, Kartoniert (TB), Englisch
- Verlag: Wiley & Sons
- ISBN-10: 0470975237
- ISBN-13: 9780470975237
- Erscheinungsdatum: 27.09.2013
Sprache:
Englisch
Kommentar zu "Bioinorganic Chemistry: Inorganic Elements in the Chemistry of Life"
0 Gebrauchte Artikel zu „Bioinorganic Chemistry: Inorganic Elements in the Chemistry of Life“
| Zustand | Preis | Porto | Zahlung | Verkäufer | Rating |
|---|
Schreiben Sie einen Kommentar zu "Bioinorganic Chemistry: Inorganic Elements in the Chemistry of Life".
Kommentar verfassen