Biology of Negative Strand RNA Viruses: The Power of Reverse Genetics
(Sprache: Englisch)
Negative-strand RNA viruses, so named because of the polarity of their genomic RNA to mRNA, include important human and non-human pathogens. This volume covers major advances in reverse genetics techniques over the past decade, state-of-the-art basic...
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Klappentext zu „Biology of Negative Strand RNA Viruses: The Power of Reverse Genetics “
Negative-strand RNA viruses, so named because of the polarity of their genomic RNA to mRNA, include important human and non-human pathogens. This volume covers major advances in reverse genetics techniques over the past decade, state-of-the-art basic science and the clinical implications of experimental findings. This should rekindle interest in negative-strand RNA viruses among readers, including those in other disciplines, leading to further progress in understanding these important viruses and in developing effective measures of control.
Inhaltsverzeichnis zu „Biology of Negative Strand RNA Viruses: The Power of Reverse Genetics “
Introduction.- Reverse genetics of mononegavirales.- Reverse systems for the generation of segmented negative-sense RNA viruses entirely from cloned cDNA.- Transcription and replication of non-segmented negative strand RNA viruses.- Orthomyxovirus replication, transcription, and polyadenylation.- Escaping from the cell: assembly and budding of negative-strand RNA viruses.- Accessory genes of the paramyxoviridae, a large family of nonsegmented negative strand RNA viruses, as a focus of active investigation by reverse genetics.- Identification and characterization of viral antagonists of type I interferon in negative-strand RNA viruses.- Towards multivalent vaccines and therapeutic viruses.- Influenza vaccines generated by reverse genetics.- Subject index
Bibliographische Angaben
- 2004, 350 Seiten, mit farbigen Abbildungen, Maße: 16 x 24,1 cm, Gebunden, Englisch
- Herausgegeben von Kawaoka, Yoshihiro
- Herausgegeben: Yoshihiro Kawaoka
- Verlag: Springer
- ISBN-10: 3540406611
- ISBN-13: 9783540406617
- Erscheinungsdatum: 07.05.2004
Sprache:
Englisch
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