Brain Chemistry and Mental Disease

Enzymes: Implications in Mental Disease.- Multiple Forms of Monoamine Oxidase in Developing Tissues: The Implications for Mental Disorder.- Regulation of Catecholamine Biosynthesis: Tyrosine Hydroxylase and Dihydropteridine Reductase.- Behavioral, Metabolic, and Enzymatic Studies of a Brain Indoleethylamine N-Methylating System.- Transmethylation Processes in Schizophrenia.- Psychoactive Agents: Biological Actions.- Effects of Drugs on Catecholamine Synthesis.- Pharmacological Implications of the Effects of Amphetamine and Its Analogs on the Turnover Rate of Tissue Catecholamines.- Studies on the Mechanism of Action of 6-Methoxytetrahydro-Beta-Carboline in Elevating Brain Serotonin.- Comparison of the Effects of Electrical Stimulation and Iontophoretic Dopamine on Neurons of the Nigro-Neostriatal Pathway.- Biological Aspects of Affective Disorders.- Biogenic Amines and Affective Disorders.- Catecholamines and Affective Illness: Studies with L-DOPA and Alpha-Methyl-Para-Tyrosine.-Relationships between Stress and Brain 5-Hydroxy-tryptamine and their Possible Significance in Affective Disorders.- Interactions between Adrenocortical Steroid Hormones, Electrolytes, and the Catecholamines.- Thyroid-Imipramine Interaction: Clinical Results and Basic Mechanism.- Effects of Tricyclic Antidepressants on Norepinephrine Metabolism: Basic and Clinical Studies.- Brain Amines and Affective Disorders.- Overall Review.- Panel Discussion.- Genetic and Metabolic Factors in Mental Disorders.- Heterogeneous Distributions of Schizophrenia.- Frequency of Genetic Polymorphism: Implications for Mental Disease.- Purine Metabolism and Abnormal Behavior in Children.- Modern Concepts of Chemotherapy.- Chemotherapy of Schizophrenia.- Chemotherapy of Manic-Depressive Disorder.- I. Introduction.- II. Chemotherapy of Mania.- III. Prophylaxis Against Manic and Depressive Relapses.- IV. Behavioral Toxicity.- V. Psychoactive Drugs Versus Other Forms of Therapy.- VI. Psychoactive Drug Choice.- VII.