Brain Ischemia

Section I: The Brain.- Prefatory Comments.- 1. Mechanisms of Cell Death in Ischemia.- 2. Positron Emission Tomography (PET) in Acute Ischemic Stroke: Pathophysical and Clinical Implications.- 3. Excitotoxicity and Stroke.- 4. Growth Factors in Stroke.- 5. Ischemic Cerebral Edema.- Concluding Comments.- Section II: The Eye.- Prefatory Comments.- 6. Ocular Ischemia.- Concluding Comments.- Section III. The Blood.- Prefatory Comments.- 7. Coagulation.- 8. Immunohematologic Mechanisms in Stroke.- 9. Fibrinolysis and its Relevance to Acute Focal Cerebral Ischemia.- Concluding Comments.- Section IV: The Blood Vessels.- Prefatory Comments.- 10. Atherosclerosis.- 11. Cerebral Vasoconstriction: Physiology, Pathophysiology and Occurrence in Selected Cerebrovascular Disorders.- 12. Endothelial Cells and Cerebrovascular Disease.- 13. Physical Factors in the Pathogenesis of Atheroma Formation.- 14. Microvascular Pathology.- Concluding Comments.- Section V: Blood Flow, Blood Pressure and Intracranial Pressure.- Prefatory Comments.- 15. Autoregulation, Hypertension and Regulation of the Cerebral Circulation.- 16. The Innervation of Pial Blood Vessels and their Role in Cerebrovascular Regulation.- 17. Rheology of Flow and its Effects.- 18. Pathophysiology of Raised Intracranial Pressure.- 19. Central Neurogenic Regulation of Regional Cerebral Blood Flow (rCBF) and Relationship to Neuroprotection.- Concluding Comments.- Section VI: The Heart.- Prefatory Comments.- 20. Cardiac Disease and Embolic Sources.- 21. Heart and Brain Relationships.- Concluding Comments.- Section VII: Clinical Research: Epidemiology, Statistics, Databases and Trials.- Prefatory Comments.- 22. Epidemiology and Trials.- 23. Stroke Databanks and Stroke Registries.- Concluding Comments.

Brain Ischemia: Basic Concepts and Clinical Relevance presents a well-planned, integrated, and cohesive approach which is often absent from other multi-authored compendia. It is an invaluable overview of current thought in this very exciting and pivotal time in the history of the care of stroke patients and stroke research.