Cancer
(Sprache: Englisch)
This volume reviews advances in cancer chemotherapy research over the last 10 years. Chapters written by leading experts in their field reflect a range of current medicinal chemistry approaches to small molecule drugs. Each chapter covers the drug target...
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This volume reviews advances in cancer chemotherapy research over the last 10 years. Chapters written by leading experts in their field reflect a range of current medicinal chemistry approaches to small molecule drugs. Each chapter covers the drug target and biological rationale, chemotypes, clinical status and future prospects in this rapidly developing area of drug research.
Klappentext zu „Cancer “
This volume reviews advances in cancer chemotherapy research over the last 10 years. Chapters written by leading experts in their field reflect a range of current medicinal chemistry approaches to small molecule drugs. Each chapter covers the drug target and biological rationale, chemotypes, clinical status and future prospects in this rapidly developing area of drug research.
The last decade has seen a dramatic shift in anticancer drug research towards agents that aim to target selectively key regulatory and signaling processes known to drive tumorigenesis. A number of these newer agents have now been introduced into clinical practice. This volume reviews advances in cancer chemotherapy research over the last 10 years and will be of interest to scientists engaged in drug research in the pharmaceutical industry, biotechnology and startup companies, academia and government institutions. Chapters written by leading experts in their field reflect a range of current medicinal chemistry approaches to small molecule drugs, including anti-hormonal therapy, growth factor inhibition, survival signaling, cell cycle inhibition, anti-angiogenics and anti-nvasives. Each chapter aims to cover the drug target and biological rationale, chemotypes, clinical status and future prospects in this rapidly developing area of drug research.
Inhaltsverzeichnis zu „Cancer “
- R. Bradbury: Overview- J. Hoffmann: Antihormonals
- E. Wallace et al.: Growth Factor Inhibition
- P. Angibaud et al.: Farnesyl Transferase Inhibition
- C. Garcia-Cheverria et al.: Survival Signalling
- R.A. Galemmo Jr et al.: Cell Cycle
- K. van Emelen et al.: Chromatin Modification (HDAC)
- R. Borzilleri, L. Lombardo: Angiogenesis (VEGFR)
- T. Sawyer: Anti-invasives: Src and Related Metastasis Therapeutic Targets
- D. Boschelli: Anti-invasives: Bcr-Abl
Bibliographische Angaben
- 2007, 452 Seiten, mit farbigen Abbildungen, Maße: 16,2 x 24,3 cm, Gebunden, Englisch
- Herausgegeben:Bradbury, Rob
- Herausgegeben: Rob Bradbury
- Verlag: Springer
- ISBN-10: 3540331190
- ISBN-13: 9783540331193
Sprache:
Englisch
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