Cerebrospinal Fluid in Neurologic Disorders

possesses state of the art technologies, such as SOMAscan, Quanterix ultrasensitive SimOA technology, Mesoscale technology and in vitro technologies for clinical routine lab analysis. These studies are all based on the availability of a well-characterised biobank, headed by me, of >4000 paired CSF and serum samples of dementia patients (a.o. Alzheimer, Frontotemporal, Lewy Bodies) and controls with subjective complaints, that visit the Alzheimer Center Amsterdam outpatient clinic. To ensure the quality of biosamples, Teunissen performs scientific studies to detect e.g. sentinel biomarkers, and take the lead in guideline development for CSF biomarker study methodology. Teunissen has always collaborated strongly in the field, as this is a prerequisite for performing high quality biomarker studies, visible in her lead in the BioMS network, the Society for Neurochemistry and routine CSF analysis, and the Alzheimer Association-global biomarker standardization consortium. Dr. Tumani received his medical degree from the University of Göttingen/Germany in 1991. He received Board certification in Neurology in 1999, and completed his professorship thesis in 2001 on the topic "physiology and clinical relevance of brain-specific proteins in CSF”.
Dr. Tumani is Professor of Neurology and Director of Multiple Sclerosis Center at the Dept. of Neurology of the University School of Medicine, in Ulm/Germany. He is also the Director of the CSF laboratory, and past President of the "German Society of CSF analysis and clinical neurochemistry” (DGLN). Since 2015, he is also Chief of the Clinic of Neurology Dietenbronn in Schwendi/Germany specialized for diagnostics and treatment of neuroinflammatory and neurodegenerative disorders.
Dr. Tumani has published over 200 peer-reviewed original papers and over 20 book chapters, and he is a reviewer for several journals and research funding agencies. His scientific areas of interest include diagnostic and prognostic biomarkers in neuroinflammatory as well as neurodegenerative diseases. Dr. Tumani has served as principal investigator on several multi-center clinical trials.
Dr. Tumani's research has been funded by the Hertie-Foundation, German Research Foundation (DFG), Federal Ministry of Education and Research (BMBF), Faculty of University of Ulm, Polyradikulitis-Stiftung, and the pharmaceutical industry.
Affiliations and Expertise: Department of Neurology, University of Ulm, Germany