Comparative Genomics

Reconstructing Domain Compositions of Ancestral Multi-domain Proteins.- Domain Architecture in Homolog Identification.- Inferring Positional Homologs with Common Intervals of Sequences.- On Genome Evolution with Accumulated Change and Innovation.- Paths and Cycles in Breakpoint Graphs of Random Multichromosomal Genomes.- Common Intervals and Symmetric Difference in a Model-Free Phylogenomics, with an Application to Streptophyte Evolution.- How Pseudo-boolean Programming Can Help Genome Rearrangement Distance Computation.- Sorting by Translocations Via Reversals Theory.- Inferring Gene Orders from Gene Maps Using the Breakpoint Distance.- Ordering Partially Assembled Genomes Using Gene Arrangements.- Evolution of Tandemly Repeated Sequences Through Duplication and Inversion.- A PQ Framework for Reconstructions of Common Ancestors and Phylogeny.- Intron Loss Dynamics in Mammals.- Finding Maximum Likelihood Indel Scenarios.- Conservation Patterns in cis-Elements Reveal Compensatory Mutations.- Transcription Factor Centric Discovery of Regulatory Elements in Mammalian Genomes Using Alignment-Independent Conservation Maps.- Identifiability Issues in Phylogeny-Based Detection of Horizontal Gene Transfer.

From the reviews: "Comparative genomics is an exciting new field of bioinformatics dealing with problems of vital importance for many areas in biology. ! This volume contains the 17 fully refereed papers presented at the fourth meeting, held in Montreal in September 2006. ! I consider this book essential for libraries aiming to support research in any field of bioinformatics." (N. Sapidis, ACM Computing Reviews, Vol. 49 (4), April, 2008)