Current Topics in Coronary Research

Section 1: Metabolic Control of Coronary Blood Flow.- Challenges to the Adenosine Hypothesis for the Regulation of Coronary Blood Flow.- Observations on the Effect of Changes in Arterial Oxygenation on Adenosine Induced Coronary Vasodilatation.- Adenosine Metabolism: Properties of Dog Heart Microsomal 5?-Nucleotidase.- Myocardial: Blood Purine Nucleoside Concentration Ratios in Canine Myocardium.- Role of O2 in Control of the Coronary Capillary Reserve.- Coronary and Systemic Hemodynamics in Chemically Sympathectomized Dogs.- Discussion.- Section 2: Transmural Myocardial flow Gradients.- Factors Determining the Distribution and Adequacy of Left Ventricular Myocardial Blood Flow.- Regional Changes in Intramyocardial Pressure Following Myocardial Ischemia.- Discussion.- Section 3: Coronary Collateral Circulation.- Some Developments in the Concept of Collateral Circulation to the Myocardium.- Viewpoint of a Human Pathologist on the Current Coronary Problem.- The Distribution of Coronary and of Coronary Collateral Flow in Normal Hearts and After Chronic Coronary Occlusion.- Local Oxygen Tension and Blood Flow in the Normal and Chronic Ischemic Myocardium in the Anesthetized Dog.- Hemodynamic Evidence of the Development of Coronary Collateral Circulation in Conscious Dogs.- The Effect of Glyceryl Trinitrate on Coronary Collateral Flow - A Preliminary Report.- Discussion.- Section 4: Clinical Problems in the Coronary Circulation.- Relation of Coronary Events to Spasm of Coronary Arteries, Precariousness of Obstructive Lesions and Availability of Collateral Channels.- Vein Bypass Surgery for Ischemic Heart Disease Perspective - March, 1973.- Clinical Studies in the Selection of Patients for Coronary-Artery Surgery.- Coronary Artery Bypass.- Effects of Aorta-CoronaryBypass Grafts on Myocardial Contractile State: Response to Catecholamine Stress.- Coronary Artery Reperfusion: Early Effects on Coronary Hemodynamics.- Discussion.- Author Index.