Evidence-Based Hematology

About the Contributors.
 
Preface.
 
Part I: A Guide to the Evidence.
 
1. Rating the quality of evidence and making recommendations
 
2. An overview of systematic reviews
 
3. Interpreting results of clinical research
 
4. Finding the evidence
 
5. Applying EBM in clinical practice
 
6. Using evidence to guide the diagnosis of disease
 
Part II
 
7. Diagnosis of Deep Vein Thrombosis
 
8. Diagnosis of Pulmonary Embolism
 
9. Initial Therapy of Deep Vein Thrombosis and Pulmonary Embolism
 
10. Long-term Anticoagulation in Venous Thromboembolism
 
11. Thrombolytic Therapy for Deep Vein Thrombosis and Pulmonary Embolism
 
12. Inferior Vena Cava Interruption
 
13. Management of Venous Thromboembolism in Pregnancy
 
14. Pediatric Thrombosis
 
15. Bridging Anticoagulation in Patients who Require
 
16. Evidence-based approach to the diagnosis and management of thrombotic thrombocytopenic purpura
 
17. Diagnosis and Management of Disseminated Intravascular Coagulation
 
18. Diagnosis and Management of Hereditary Bleeding Disorders
 
19. Diagnosis and Management of Acquired Bleeding Disorders
 
20. Diagnosis and Management of Heparin-Induced Thrombocytopenia
 
21. Management of Antiphospholipid Antibody Syndrome
 
Part III
 
22. Clinical Questions in iron overload
 
23. Aplastic Anemia
 
24. Acquired Anemias
 
25. Immune thrombocytopenic purpura
 
26. Neutropenia
 
27. Hypereosinophilia
 
28. Porphyrias
 
29. Membrane and Enzyme Abnormalities of the Erythrocyte
 
30. Sickle cell disease
 
31. Evidence-based treatment of thalassemia major
 
Part IV
 
32. Acute Lymphoblastic Leukemia in Adults
 
33. Acute Myeloblastic Leukemia in Adults
 
34. Acute Myeloid Leukemia in Adults
 
35. Current Areas of

Dr Mark Crowther is Associate Professor of Medicine and Program Director of the Adult Hematology Residency Training Program at McMaster University. He is a member of the Canadian Critical Care Trials Group.

Dr. Jeffrey Ginsberg is a leading expert in the diagnosis, prevention and management of venous thromboembolism and has led many of the "practice changing" studies published in this area in the last 20 years. He is the recipient of numerous awards and distinctions, most recently an endowed chair at McMaster University allowing him to pursue further research in venous and arterial thrombosis.

Dr. Holger Schünemann is a leading expert in evidence based practice with a particular interest in the development and widespread dissemination of validated evidence scoring criteria. Dr. Schünemann has played an important role in the evolution of evidence based guidelines currently written by organizations such as the American College of Chest Physicians and the American Thoracic Society.

Dr. Ralph Meyer has recently joined the National Cancer Institute of Canada after a distinguished career at McMaster University. Dr. Meyer is responsible for administering the Clinical Trial Program at the NCIC. The NCIC has led or participated in many national and international studies which guide current best treatment practices for disorders such as Hodgkin's disease, multiple myeloma and other hematologic malignancies.

Dr. Richard Lottenberg is a professor of medicine and past Division Chair of the division of Hematology and Oncology. He is currently the Training Program Director at the University of Florida and is widely regarded as an expert in the evidence based management of sickle cell anemia.

"This book is an excellent collection of current best practices in hematology. It should appeal to all who have to deal with everyday challenges in blood diseases." (Journal of Tropical Pediatrics, June 2009)