Genomic Medicine
A Practical Guide
(Sprache: Englisch)
The field of Molecular Diagnostics is rapidly evolving and molecular characterization of neoplasms is becoming an increasingly important part of the pathologic work up and diagnosis of many tumor types. This work provides a high-yield reference book that...
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Klappentext zu „Genomic Medicine “
The field of Molecular Diagnostics is rapidly evolving and molecular characterization of neoplasms is becoming an increasingly important part of the pathologic work up and diagnosis of many tumor types. This work provides a high-yield reference book that compiles critical information related to molecular biomarkers for various solid tumor and hematologic malignancy subtypes. It is succinct yet comprehensive enough to be suitable for fellows in training and medical professionals with an interest in molecular pathology and biomarkers. The book covers many aspects of molecular diagnostics, from techniques to applications and comprehensive summaries of the current molecular biomarkers of critical importance in solid and liquid tumors. Attention is also specifi cally devoted to bioinformatics and next generation sequencing, as well as pre-analytical issues that must be considered for accurate interpretation of molecular results in the context of overall patient care.This text focuses on clinical utility and validity and serves as an "owner's manual" in Genomic Diagnostics for the practicing pathologist, pathology fellows and residents and other health care providers. Physicians will find this book invaluable as a quick reference for current molecular testing modalities and guidelines, tumor board preparation, deciding which test to order and interpreting genomic laboratory results. In addition, it is an accessible for trainees as a board review preparation reference.
Inhaltsverzeichnis zu „Genomic Medicine “
PREFACELaura J. Tafe, MD and Maria E. Arcila, MD
PART I: GENERAL CONCEPTS
Chapter 1: Pre-Analytics, Current Testing Technologies, and Limitations of Testing
Alejandro Luiña Contreras, MD; Jose Jasper C. Andal, MD; Raymundo Lo, MD; Daphne Chua Ang, MD
Chapter 2: Next Generation Sequencing
Alanna J. Church, M.Sc., M.D.
Chapter 3: Cell Free DNA Testing
Brennan Decker, MD, PhD and Lynette M. Sholl, MD
Chapter 4: Role of Bioinformatics in Molecular Medicine
Chad Vanderbilt, M.D., Sumit Middha, Ph.D.
Chapter 5: Interpreting Genomic ReportsAlejandro Luiña Contreras, M.D.
PART II: APPLICATIONS IN SOLID TUMORS
Chapter 6: Lung Carcinoma Maria E Arcila, Jason C Chang, Laura J Tafe
Chapter 7: GI including GIST
Efsevia Vakiani, MD, PhD
Chapter 8: Breast
Dara S. Ross, MD
Chapter 9: Genitourinary Tumors
Marie-Lisa Eich and George J. Netto
Chapter 10: Gynecologic Malignancies
Jessica L. Dillon, MD and Laura J. Tafe, MD
Chapter 11: Sarcomas
Konstantinos Linos MD, FCAP, FASDP
Chapter 12: Salivary Gland Carcinomas
Snjezana Dogan, MD
Chapter 13: Sinonasal Carcinomas
Snjezana Dogan, MD
PART III: APPLICATIONS IN HEMATOPATHOLOGY
Chapter 14: Acute Myeloid Neoplasms
Eric Y. Loo, MD
Chapter 15: Chronic Myeloid Neoplasms
Maria E. Arcila and Caleb Ho
Chapter 16: Lymphomas
Vignesh Shanmugam, MD and Annette S. Kim, MD, PhD
Autoren-Porträt
Laura J. Tafe, MDAssociate Professor of Pathology and Laboratory MedicineDepartment of Pathology and Laboratory MedicineDartmouth-Hitchcock Medical CenterOne Medical Center DriveLebanon, NH 03756603-650-7211Maria E. Arcila, MDAssociate attending Department of Pathology - Hematopathology and Molecular Diagnostics Services Memorial Sloan Kettering Cancer Center 1275 York AveNew York, NY 10065212 6397879
Bibliographische Angaben
- 2019, 1st ed. 2020, X, 325 Seiten, 20 farbige Abbildungen, Maße: 15,9 x 24,1 cm, Gebunden, Englisch
- Herausgegeben: Laura J. Tafe, Maria E. Arcila
- Verlag: Springer, Berlin
- ISBN-10: 3030229211
- ISBN-13: 9783030229214
Sprache:
Englisch
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