Glucose-sensing Receptor in Pancreatic Beta-cells
(Sprache: Englisch)
Since the 1970s, there has been much discussion about the ¿glucoreceptor¿ and ¿substrate site¿ and which of these two is the dominant theory, but new findings on the glucose-sensing receptor have now shed new light on the ¿glucoreceptor theory.¿ This volume...
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Since the 1970s, there has been much discussion about the ¿glucoreceptor¿ and ¿substrate site¿ and which of these two is the dominant theory, but new findings on the glucose-sensing receptor have now shed new light on the ¿glucoreceptor theory.¿ This volume reviews recent advances concerning the glucose-sensing receptor in pancreatic beta-cells.The history of research into pancreatic beta-cells is long and complex; accordingly, the first chapters present the history of this field and explain the hypothesis of insulin secretion mechanisms: ¿glucoreceptor theory¿. Subsequent chapters examine the function and activity of the glucose-sensing receptor in pancreatic beta-cells, such as identification, channel pathway, receptor signal and physiological role. Readers will gain a thorough understanding of the glucose-sensing receptor and glucose metabolism in pancreatic beta-cells, new insights into the pathophysiology of diabetes, and learn about new targets for the treatment of diabetes.
Inhaltsverzeichnis zu „Glucose-sensing Receptor in Pancreatic Beta-cells “
.-1 HISTORY OF THE RESEARCH ON THE GLUCOSE RECEPTOR.-2Cell-surface Glucoreceptor Recognizing Anomers of Glucose in Pancreatic b-cells.-3KATP CHANNEL-INDEPENDENT PATHWAY and THE GLUCORECEPTOR.-4Signaling System Activated by the Glucose-sensing Receptor.-5The Role of the Glucose-sensing Receptor in Glucose-induced Insulin Secretion in Pancreatic b-cells
Autoren-Porträt
Itaru Kojima, M.D. Professor Emeritus Institute for Molecular & Cellular Regulation, Gunma University
Bibliographische Angaben
- 2019, 1st ed. 2018, V, 71 Seiten, 7 farbige Abbildungen, Maße: 16 x 24,1 cm, Gebunden, Englisch
- Herausgegeben: Itaru Kojima
- Verlag: Springer, Berlin
- ISBN-10: 9811300011
- ISBN-13: 9789811300011
Sprache:
Englisch
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