High-Throughput Screening in Drug Discovery
(Sprache: Englisch)
Discover the latest improvements to compound screening in pharmaceutical research and chemical biology, including the chemoinformatic tools needed for proper data evaluation. With contributions by leading pharmaceutical companies from the US and Europe.
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Produktinformationen zu „High-Throughput Screening in Drug Discovery “
Discover the latest improvements to compound screening in pharmaceutical research and chemical biology, including the chemoinformatic tools needed for proper data evaluation. With contributions by leading pharmaceutical companies from the US and Europe.
.
.
Klappentext zu „High-Throughput Screening in Drug Discovery “
Backed by leading authorities, this is a professional guide to successful compound screening in pharmaceutical research and chemical biology, including the chemoinformatic tools needed for correct data evaluation. Chapter authors from leading pharmaceutical companies as well as from Harvard University discuss such factors as chemical genetics, binding, cell-based and biochemical assays, the efficient use of compound libraries and data mining using cell-based assay results.For both academics and professionals in the pharma and biotech industries working on small molecule screening.
Inhaltsverzeichnis zu „High-Throughput Screening in Drug Discovery “
Chemical Genetics (C. Shamu, Harvard University)High-Throughput Screening for Targeted Drug Discovery (J. Hüser, Bayer Healthcare)
Laboratory Automation (J. Comley, Cambridge, UK)
Binding Assays (L. Mayr, Novartis Pharma)
Cell-based Assays (S. Rees, GlaxoSmithKline)
Biochemical Assays (W. Mallender, Millennium Pharmaceuticals)
High-Content Screening (P. Lipp, University of Homburg/Saar)
Handling and Management of Primary Assay Data (H. Gubler, Novartis Pharma)
Chemoinformatic Tools for HTS Data Analysis (S. Mundt, Bayer HealthCare)
Efficient Use of Compound Libraries: Random Screening vs. Focused Libraries (M. Beck, Bayer CropScience)
Data Mining Using Cell-Based Assay Results (J. Caldwell, Novartis Institute)
Autoren-Porträt
Dr. Jörg Hüser is Director of HTS Technologies at the Healthcare Division of Bayer AG in Wuppertal (Germany).
Bibliographische Angaben
- 2006, XVIII, 344 Seiten, 13 farbige Abbildungen, 129 Schwarz-Weiß-Abbildungen, Maße: 17,6 x 24,7 cm, Gebunden, Englisch
- Herausgegeben: Jörg Hüser, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers
- Verlag: Wiley-VCH
- ISBN-10: 3527312838
- ISBN-13: 9783527312832
- Erscheinungsdatum: 06.09.2006
Sprache:
Englisch
Rezension zu „High-Throughput Screening in Drug Discovery “
"...ein professioneller Leitfaden für erfolgreiche Wirkstoff-Screenings, der sich an Forscher in Planung wie auch in laufenden Screenings richtet."Chemiereport.at
Pressezitat
"...ein professioneller Leitfaden für erfolgreiche Wirkstoff-Screenings, der sich an Forscher in Planung wie auch in laufenden Screenings richtet."Chemiereport.at
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