Highlights in Bioorganic Chemistry

STRUCTURE OF BIOMOLECULESb-amino acids in Nature: Biosynthesis and BiologyArtificial receptors for the stabilization of b-sheet structuresConformational equilibria of RNAConformational restriction of sphingolipidsStabilization of peptide-microstructures by coordniation of metal ionsSynthesis and application of proline and piccolic acid derivatives: tools for stabilization of peptide secondary structures.INTERMOLECULAR INTERACTIONS (BINDING)Artificial rotary motors at the molecular levelCarbohydrate recognition by artificial receptorsSynthetic approaches to study carbohydrate-lectin interactionsCyclopeptides as macrocyclic host molecules for charged guestsCombinatorial chemistry as a tool for the development of molecular receptors for small peptidesThe design of new binding motifs for c-terminal peptidesINTERACTION OF SMALL MOLECULES WITH BIOLOGICAL SYSTEMS (FUNCTION)Modulation of biochemical processes by synthetic hosts for substratesInteraction of NO and peroxynitrite with hemoglobin and myoglobinOxidative splitting of pyrimidine cyclobutane dimersInhibitors against human mast-cell-tryptase: a potential approach to attack asthma?Selectivity of DNA replicationAcridizinium salts and their photophysical interaction with DNADNA-detection in homogeneous solution

Carsten Schmuck is Professor of Organic Chemistry at the University of Würzburg. He studied chemistry and obtained his PhD at the Ruhr-University in Bochum. After a postdoctorate at Columbia University in New York, he carried out his Habilitation at the University of Cologne and joined the Unviersity of Würzburg as associate professor in 2002.
Helma Wennemers is Professor of Organic Chemistry at the University of Basel. She studied chemistry at the Johann Wolfgand Goethe-University in Frankfurt and obtained her PhD at the Columbia University in New York. After a postdoctorate at Nagoya University in Japan she joined the University of Basel as assistant professor and was promoted to associate professor in 2003.

"Die Mehrzahl der Artikel sind lesenswert, leicht verständlich und bieten einen guten Überblick über das jeweilige Thema, ohne sich in Details zu verlieren. "Highlights in Bioorganic Chemistry" ist für jeden von Interesse, der sich für Bioorganik interessiert, denn das Buch zeigt die ganze Themenvielfalt auf."www.organische-chemie.ch3.3.04"Für Leser mit profunden Kenntnissen in organischer Chemie und Biochemie ist dieses Werk eine gut aufbereitetet Übersicht der aktuellen Entwicklung dieser Forschungsdisziplin und somit eine ideale Ergänzung zu Standard-Lehrbüchern. Viel Freude beim Entdecken spannender Ideen!" BioTec - Fachmagazin für Biotechnologie

"...gives the average reader, on reading the contents, a general perspective of the scope of present-day bioorganic chemistry..."Chemistry and Industry, August 2004"The book consists of 35 chapters on various aspects of our chemical knowledge of various biological assemblies or of their model counterparts. The chapters have been written by various experts in the field, and I am naturally very stimulated by the state-of-the-art coverage that these colleagues have so nicely given to various aspects in a very professional manner. I have no doubt that the book will be helpful and interesting to both, beginners in the bioorganic research as well as to those who are practitioners in the field as a readily availabele reference book. ... This is a good, affordable reference book with plenty of citations to the review articles and original publications. I strongly recommend this as a reference or handbook to my both young and expert colleagues."Jyoti Chattopadhyaya, Uppsala University, Sweden, ChemBioChem. 12/2004"...should be found on the shelves of all chemistry libraries." Journal of the American Chemical Society, January 26, 2004