Host-Bacteria Interactions

Galleria mellonella as an Infection Model for Select Agents.- Drosophila as a Model for Intestinal Infections.- Zebrafish Embryos as a Model to Study Bacterial Virulence.- Studying Host-pathogen Interaction Events in Living Mice Visualized in Real Time using Biophotonic Imaging.- Intravital Two photon Imaging to Understand Bacterial Infections of the Mammalian Host.- Cre Reporter Assay for Translocation (CRAfT), A Tool for the Study of Protein Translocation into Host Cells.- Detection of the Interaction Between Host and Bacterial Proteins: Eukaryotic Nucleolin Interacts with Francisella Elongation Factor Tu.- Hijacking the Host Proteasome for the Temporal Degradation of Bacterial Effectors.- Life Cell Imaging of Phosphoinositide Dynamics during Legionella Infection.- Investigating Interference with Apoptosis Induction by Bacterial Proteins.- Bimolecular Fluorescence Complementation for Imaging Protein Interactions in Plant Hosts of Microbial Pathogens.- Investigating TLR Signalling Responses in Murine Dendritic Cells upon Bacterial Infection.- siRNA Screens using Drosophila Cells to Identify Host Factors Required for Infection.- Purification of Intracellular Bacteria: Isolation of Viable Brucella abortus from Host Cells.- RNA Sequencing of FACS-sorted Immune Cell Populations from Zebrafish Infection Models to Identify Cell Specific Responses to Intracellular Pathogens.- Taking the Shortcut for High-throughput Shotgun Proteomic Analysis of Bacteria.- Comparative Genomic Analysis at the PATRIC, a Bioinformatic Resource Center.- A Markerless Deletion Method for Genetic Manipulation of Burkholderia cenocepacia and Other Multi Antibiotic Resistant Gram-negative Bacteria.- Gene Inactivation in Coxiella burnetii.- A Chemical Mutagenesis Approach to Identify Virulence Determinants in the Obligate Intracellular Pathogen Chlamydia trachomatis.