How the Immune System Recognizes Self and Nonself
Immunoreceptors and Their Signaling
(Sprache: Englisch)
This book surveys receptors used by immune cells, how they recognize self, nonself and "neoself" components, and how the immune system distinguishes the self and nonself - a far more complex process than a computer security system detecting infected documents.
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This book surveys receptors used by immune cells, how they recognize self, nonself and "neoself" components, and how the immune system distinguishes the self and nonself - a far more complex process than a computer security system detecting infected documents.
Klappentext zu „How the Immune System Recognizes Self and Nonself “
The immune system is a highly evolved security system that protects the body from infection by pathogens such as viruses and bacteria. The immune system also recognizes and rejects a transplanted organ from even the same species. Indeed, the immune system potentially recognizes and eliminates everything that invades the body (nonself). However, it does not normally eliminate self cells or tissues except tumor cells developed from self tissue. Occasionally the immune system breaks down and attacks the body components of the self, manifesting as autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus, myasthenia gravis, and insulin-resistant diabetes. This book contains extensive updated reviews describing what kinds of receptors various immune cells use, how they recognize the self and the nonself components (and "neoself" such as tumors), and how finally the immune system distinguishes the self and nonself - a far more complicated process than a computer security system detecting infected documents. Perfect understanding of this system should make it possible in the future to regulate immunity to transplants, to cure autoimmune disease and allergy, and to facilitate tumor immunity.
Inhaltsverzeichnis zu „How the Immune System Recognizes Self and Nonself “
1. Recognition of Pathogens: Toll-Like Receptors Satoshi Uematsu and Shizuo Akira 2. Strategies of Natural Killer (NK) Cell Recognition and Their Roles in Tumor Immunosurveillance C. Andrew Stewart and Eric Vivier 3. Recent Progress on Paired Immunoglobulin-Like Receptors Hiromi Kubagawa, Ching-Cheng Chen, Ikuko Torii, Max D. Cooper, Kyoko Masuda, Yoshimoto Katsura, and Hiroshi Kawamoto 4. Self-nonself Recognition through B-Cell Antigen Receptor Daisuke Kitamura 5. How Do T Cells Discriminate Self from Nonself? Catherine Mazza and Bernard Malissen 6. Fc Receptors Falk Nimmerjahn and Jeffrey V. Ravetch 7. Self and Nonself Recognition by Coreceptors on B Lymphocytes: Regulation of B lymphocytes by CD19, CD21, CD22, and CD72 Kozo Watanabe and Takeshi Tsubata 8. Co-Receptors in the Positive and Negative Regulation of T-Cell Immunity Helga Schneider and Christopher E. Rudd
Bibliographische Angaben
- 2007, 251 Seiten, 6 farbige Abbildungen, 24 Schwarz-Weiß-Abbildungen, Maße: 16 x 24,1 cm, Gebunden, Englisch
- Herausgegeben: Daisuke Kitamura
- Verlag: Springer
- ISBN-10: 4431738835
- ISBN-13: 9784431738831
- Erscheinungsdatum: 20.11.2007
Sprache:
Englisch
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