Human Fungal Pathogen Identification
Methods and Protocols
(Sprache: Englisch)
This detailed volume presents timely and authoritative content offering a comprehensive overview of the current state of the art in fungal diagnostics. Moreover, it addresses on-going developments expected to provide a basis for targeted treatment...
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Klappentext zu „Human Fungal Pathogen Identification “
This detailed volume presents timely and authoritative content offering a comprehensive overview of the current state of the art in fungal diagnostics. Moreover, it addresses on-going developments expected to provide a basis for targeted treatment strategies resulting in improved outcome of invasive mycoses. The knowledge of host-related predisposing factors and stratified treatment options facilitating timely onset of adequate antifungal therapy are critical for successful clinical management and outcome of invasive fungal disease (IFD), requiring not only rapid diagnosis of a fungal infection and identification of the causative species, but also assessment of pathogen/host factors related to pathogenicity, susceptibility, and response to treatment. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls.<div> </div><div>Authoritative and practical, Human Fungal Pathogen Identification: Methods and Protocols serves as an ideal reference for researchers investigating the ever-growing worldwide healthcare problems involving fungal infections.</div>
Inhaltsverzeichnis zu „Human Fungal Pathogen Identification “
Part I: Introductory Chapters1. Current Challenges in the Diagnosis of Fungal Infections
Cornelia Lass-Flörl
2. The Changing Epidemiology of Invasive Fungal Infections
David A. Enoch, Huina Yang, Sani H. Aliyu, and Christianne Micallef
3. Current Algorithms in Fungal Diagnosis in the Immunocompromised Host
Thomas Lehrnbecher, Karsten Becker, and Andreas H. Groll
4. Commercial Molecular Tests for Fungal Diagnosis from a Practical Point of View
Michaela Lackner and Cornelia Lass-Flörl
5. Systemic Antifungal Agents: Current Status and Projected Future Developments
Seyedmojtaba Seyedmousavi, Haleh Rafati, Macit Ilkit, Mohammad T. Hedayati, and Paul Verweij
6. Fungal-Grade Reagents and Materials for Molecular Analysis
Michael G. Lorenz, Michael Lustig, and Marina Linow
Part II: Host Susceptibility and Defense
7. Host-Derived Biomarkers for Risk Assessment of Invasive Fungal Diseases
Cristina Cunha, Samuel M. Gonçalves, and Agostinho Carvalho
8. Assessment of Immune Responses to Fungal Infections: Identification and Characterization of Immune Cells in the Infected Tissue
Florian Sparber and Salomé LeibundGut-Landmann
Part III: Screening Approaches to Fungal Pathogen Detection 9. Histopathology
Renate Kain
10. Culture-Based Techniques
Birgit Willinger
11. Serological Approaches
Barbora Weinbergerova, Iva Kocmanova, Zdenek Racil, and Jiri Mayer
12. Isolation of Nucleic Acids for Fungal DiagnosisP. Lewis White and Rosemary A. Barnes
13. Prerequisites for Control of Contamination in Fungal Diagnosis
Stefan Czurda and Thomas Lion
14. Broad-Spectrum Molecular Detection of Fungal Nucleic Acids by PCR-Based Amplification Techniques
Stefan Czurda and Thomas Lion
15. Genus- and Species-Specific PCR Detection MethodsJan
... mehr
Springer and Jürgen Löffler
16. Identification of Fungal Pathogens in Tissue Samples from Patients with Proven Invasive Infection by Fluorescence In Situ Hybridization
Ilka McCormick Smith and Volker Rickerts
17. Nuclear Magnetic Resonance Spectroscopy-Based Identification of Yeast
Uwe Himmelreich, Tania C. Sorrell, and Heide-Marie Daniel
18. T2 Magnetic Resonance for Fungal DiagnosisFainareti N. Zervou, Ioannis M. Zacharioudakis, Jaclynn Kurpewski, and Eleftherios Mylonakis
Part IV: Identification of Fungal Species
19. Fungal Species Identification by MALDI-ToF Mass Spectrometry
Oliver Bader
20. Immunological Identification of Fungal Species
Filomena Nogueira, Fabian Istel, Leonel Pereira, Michael Tscherner, and Karl Kuchler
21. The Molecular Blueprint of a Fungus by Next-Generation Sequencing (NGS)Christian Grumaz, Philipp Kirstahler, and Kai Sohn
22. Microarray Technologies in Fungal Diagnostics
Steffen Rupp
Part V: Drug Resistance Testing
23. Molecular Detection of Resistance to Echinocandins
Brunella Posteraro, Antonietta Vella, Elena De Carolis, and Maurizio Sanguinetti
24. Molecular Detection of Resistance to Azole Components
Brunella Posteraro, Antonietta Vella, Elena De Carolis, and Maurizio Sanguinetti
Part VI: Novel Experimental Approaches
25. Immune Cell-Supplemented Human Skin Model for Studying Fungal Infections
Andreas Kühbacher, Kai Sohn, Anke Burger-Kentischer, and Steffen Rupp
16. Identification of Fungal Pathogens in Tissue Samples from Patients with Proven Invasive Infection by Fluorescence In Situ Hybridization
Ilka McCormick Smith and Volker Rickerts
17. Nuclear Magnetic Resonance Spectroscopy-Based Identification of Yeast
Uwe Himmelreich, Tania C. Sorrell, and Heide-Marie Daniel
18. T2 Magnetic Resonance for Fungal DiagnosisFainareti N. Zervou, Ioannis M. Zacharioudakis, Jaclynn Kurpewski, and Eleftherios Mylonakis
Part IV: Identification of Fungal Species
19. Fungal Species Identification by MALDI-ToF Mass Spectrometry
Oliver Bader
20. Immunological Identification of Fungal Species
Filomena Nogueira, Fabian Istel, Leonel Pereira, Michael Tscherner, and Karl Kuchler
21. The Molecular Blueprint of a Fungus by Next-Generation Sequencing (NGS)Christian Grumaz, Philipp Kirstahler, and Kai Sohn
22. Microarray Technologies in Fungal Diagnostics
Steffen Rupp
Part V: Drug Resistance Testing
23. Molecular Detection of Resistance to Echinocandins
Brunella Posteraro, Antonietta Vella, Elena De Carolis, and Maurizio Sanguinetti
24. Molecular Detection of Resistance to Azole Components
Brunella Posteraro, Antonietta Vella, Elena De Carolis, and Maurizio Sanguinetti
Part VI: Novel Experimental Approaches
25. Immune Cell-Supplemented Human Skin Model for Studying Fungal Infections
Andreas Kühbacher, Kai Sohn, Anke Burger-Kentischer, and Steffen Rupp
... weniger
Bibliographische Angaben
- 2016, 1st ed. 2017, XI, 453 Seiten, 49 farbige Abbildungen, Maße: 18,3 x 26 cm, Gebunden, Englisch
- Herausgegeben: Thomas Lion
- Verlag: Springer, Berlin
- ISBN-10: 1493965131
- ISBN-13: 9781493965137
- Erscheinungsdatum: 12.11.2016
Sprache:
Englisch
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