Imaging Mass Spectrometry
Protocols for Mass Microscopy
(Sprache: Englisch)
This book presents the protocols of IMS technology. Aimed at beginners, it offers practical details and instructions regarding the preparation of animal tissue samples, the application of a matrix, instrumental operations, data analysis, and more.
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This book presents the protocols of IMS technology. Aimed at beginners, it offers practical details and instructions regarding the preparation of animal tissue samples, the application of a matrix, instrumental operations, data analysis, and more.
Klappentext zu „Imaging Mass Spectrometry “
Addressing the widespread need for a practical guide to imaging mass spectrometry (IMS), this book presents the protocols of IMS technology. As that technology expands, research groups around the world continue its development. Pharmaceutical companies are using IMS for drug analyses to study pharmacokinetics and medical properties of drugs. Drug research and disease-related biomarker screening are experiencing greater use of this technology, with a concurrent increase in the number of researchers in academia and industry interested in wider applications of IMS. Intended for beginners or those with limited experience with IMS technology, this book provides practical details and instructions needed for immediate know-how, including the preparation of animal tissue samples, the application of a matrix, instrumental operations, and data analysis, among others. By describing the foundations of IMS, this volume contributes to the ongoing development of the field and to progress in human health.
Addressing the widespread need for a practical guide to imaging mass spectrometry (IMS), this book presents the protocols of IMS technology. As that technology expands, research groups around the world continue its development. Pharmaceutical companies are using IMS for drug analyses to study pharmacokinetics and medical properties of drugs. Drug research and disease-related biomarker screening are experiencing greater use of this technology, with a concurrent increase in the number of researchers in academia and industry interested in wider applications of IMS. Intended for beginners or those with limited experience with IMS technology, this book provides practical details and instructions needed for immediate know-how, including the preparation of animal tissue samples, the application of a matrix, instrumental operations, and data analysis, among others. By describing the foundations of IMS, this volume contributes to the ongoing development of the field and to progress in human health.
Inhaltsverzeichnis zu „Imaging Mass Spectrometry “
Chapter 1: IMS as an historical innovation.- Chapter 2: Guide to planning the sample-preparation step.- Chapter 3 Animal care and tissue sample extraction for IMS.- Chapter 4 Preparing biological tissue sections for imaging mass spectrometry.- Chapter 5 Matrix choice.- Chapter 6 Methods of matrix application.- Chapter 7 ImagePrep.- Chapter 8 Method of operating AXIMA-QIT as imaging instrument.- Chapter 9 Ion image reconstruction using BioMap software.- Chapter 10 Statistical procedure for IMS data analysis.- Chapter 11 Statistical analysis of IMS dataset with ClinProTool software.- Chapter 12 IMS of cultured cells.- Chapter 13 TLC-blot-imaging mass spectrometr.- Chapter 14 Applied Biosystems.- Chapter 15 Bruker Daltonics.- Chapter 16 Shimadzu Corporation.- Chapter 17 Waters Corporation.- Chapter 18 Comparison of SIMS and MALDI for mass spectrometric imaging.
Bibliographische Angaben
- Autoren: Soeren-Oliver Deininger , Masaru Furuta , Naoko Goto-Inoue , John S. Hammond , Takahiro Hayasaka , Daisuke Horigome
- 2010, 1st Edition., 272 Seiten, 11 farbige Abbildungen, Maße: 15,5 x 23,5 cm, Kartoniert (TB), Englisch
- Herausgegeben: Mitsutoshi Setou
- Verlag: Springer, Berlin
- ISBN-10: 4431094245
- ISBN-13: 9784431094241
Sprache:
Englisch
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