Inflammation and Immunity in Cancer
(Sprache: Englisch)
This book overviews cancer immunity from broad scientific fields, based on the concept that cancer is a sort of by-product of infection, inflammation, and host immune response. The innate and acquired arms of the immune system mainly participate in tumor...
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Klappentext zu „Inflammation and Immunity in Cancer “
This book overviews cancer immunity from broad scientific fields, based on the concept that cancer is a sort of by-product of infection, inflammation, and host immune response. The innate and acquired arms of the immune system mainly participate in tumor immune surveillance, and their activation is critically modulated by the situation of the tumor microenvironment. Many types of immune cells join the formation of the microenvironment. In particular, macrophages and dendritic cells enter the tumor mass to be main players in the inflammatory milieu of tumors. After introducing these topics, the book discusses immunotherapy for cancer patients as an outgrowth of this concept of infection and inflammation. With the contributions of leading scientists actively involved in the field of antitumor immunity study, this book encourages readers to understand the mechanism of general cancers based on inflammation and will facilitate prevention and the development of therapeutics for cancer.
Inhaltsverzeichnis zu „Inflammation and Immunity in Cancer “
- PrefaceChapter 1. Role of bone marrow-derived CCR1+ cells in colon cancer invasion and metastasis
Chapter 2. PGE2-associated inflammation and gastrointestinal tumorigenesis
Chapter 3. Regulation of tumor-associated myeloid cells by innate immune signaling
Chapter 4. The role of PIKfyve in TLR-mediated inflammation and immune responses
Chapter 5. Emerging roles of an innate immune regulator TAPE in the Toll-like receptor and RIG-I-like receptor pathways
Chapter 6. Anchorage-dependent multicellular aggregate formation induces CD44 high cancer stem cell-like phenotypes in adult T-cell leukemia/lymphoma cells
Chapter 7. Tumor-associated molecular patterns: its implication in tumoricidal inflammation
Chapter 8. Host factors involved in the propagation and pathogenesis of hepatitis C virus
Chapter 9. HCV-induced inflammation: The role of cross-talk between HCV-infected hepatocytes and stellate cells
Chapter 10. Development of immunotherapy for hepatocellular carcinoma
Chapter 11. Development of glypican-3-targeted cancer immunotherapy
Chapter 12. The vesicular traffic system in plasmacytoid dendritic cells as a target for immune regulation
Chapter 13. In vivo targeting of dendritic cells with artificial adjuvant vector cells (aAVC) as a novel cancer immunotherapy
Chapter 14. Enhancement of efficacy of WT1 peptide cancer vaccine by co-administration with immunopotentiating agents: Lessons from mouse models
Chapter 15. Regulation of antigen-presentation by dendritic cells and its application to cancer immunotherapy
Chapter 16. A new mode of CTL induction secondary to alteration of pMHCI repertoire by antigen processing defects
Chapter 17. Progress in clinical use of CCR4 antibody for regulatory T cell suppression
Chapter 18. Adjuvant Immunotherapy for cancer: Basic research to clinical bench
Chapter 19. Immunological regulation of human cancer stem cell/cancer-initiating cells (CSC/CIC)
Chapter 20. Overview on
... mehr
tumor immunology
Chapter 21. Studies on the immunotherapy with MPLA adjuvant + NewYork-Eso-1 protein or long overlapping peptides
- Epilogue
Chapter 21. Studies on the immunotherapy with MPLA adjuvant + NewYork-Eso-1 protein or long overlapping peptides
- Epilogue
... weniger
Bibliographische Angaben
- 2015, 2015, XI, 268 Seiten, 60 farbige Abbildungen, Maße: 16 x 24,1 cm, Gebunden, Englisch
- Herausgegeben: Tsukasa Seya, Misako Matsumoto, Keiko Udaka, Noriyuki Sato
- Verlag: Springer, Berlin
- ISBN-10: 4431553266
- ISBN-13: 9784431553267
- Erscheinungsdatum: 14.04.2015
Sprache:
Englisch
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