Isotopic Analysis

Preface
 
THE ISOTOPIC COMPOSITION OF THE ELEMENTS
Atomic Structure
Isotopes
Relation Between Atomic Structure and Natural Abundance of Elements and Isotopes
Natural Isotopic Composition of the Elements
 
SINGLE-COLLECTOR INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY
Mass Spectrometry
The Inductively Coupled Plasma Ion Source
Basic Operating Principles of Mass Spectrometers
Quadrupole-Based ICP-MS
Sample Introduction Strategies in ICP-MS
Spectral Interferences
Measuring Isotope Ratios with Single-Collector ICP-MS
 
MULTI-COLLECTOR INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY
Introduction
Early Multi-Collector Mass Spectrometers
Variable Multi-Collector Mass Spectrometers
Mass Resolution and Resolving Power
Three-Isotope Plots for Measurement Validation
Detector Technologies for Multi-Collection
Conclusion
 
ADVANCES IN LASER ABLATION-MULTI-COLLECTOR INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY
Precision of Isotope Ratio Measurements
Stable Signal Intensity Profiles: Why So Important?
Signal Smoothing Device
Multiple Ion Counting
Isotope Fractionation During Laser Ablation and Ionization
Standardization of the Isotope Ratio Data
 
CORRECTION OF INSTRUMENTAL MASS DISCRIMINATION FOR ISOTOPE RATIO DETERMINATION WITH MULTI-COLLECTOR INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY
Historical Introduction
Mass Bias in MC-ICP-MS
Systematics of Mass Bias Correction Models
Logic of Conventional Correction Models
Pitfalls with Some Correction Models
Integrity of the Correction Models
The Regression Model
Calibration with Double Spikes
Calibration with Internal Correction
Uncertainty Evaluation
Conclusion
 
REFERENCE MATERIALS IN ISOTOPIC ANALYSIS
Introduction
Terminology
Determination of Isotope Amount Ratios
Isotopic Reference Materials
Present Status, Related Problems, and Solutions
Conclusion and Outlook
 
QUALITY CONTROL IN ISOTOPE RATIO APPLICATIONS
Introduction
Terminology and

Frank Vanhaecke (°1966) is Professor in Analytical Chemistry at Ghent University (Belgium), where he leads the 'Atomic & Mass Spectrometry & A&MS' research unit that focuses on the determination, speciation and isotopic analysis of (trace) elements via ICP-mass spectrometry (ICPMS).One of the specific topics studied, is isotope ratio determination using single- and multi-collector ICP-MS in the context of elemental assay via isotope dilution, tracer experiments with stable isotopes and the use of small natural variations in the isotopic composition of metals and metalloids for provenance determination and for obtaining better insight into biological, environmental and geological problems. Frank is (co-)author of some 200 scientific papers in international journals, 15 book chapters and more than 350 conference presentations and is a Fellow of the Royal Society of Chemistry RSC. In 2011, he received a 'European Award for Plasma Spectrochemistry' for his contributions to the field.
 
Patrick Degryse (°1974) is Professor of Archaeometry at the department of Earth and Environmental Sciences and director of the Centre for Archaeological Sciences at the Katholieke Universiteit Leuven (Belgium). His main research efforts focus on the use of mineral raw materials in ancient ceramic, glass, metal and building stone production, using petrographical, mineralogical and isotope geochemical techniques. He teaches geology, geochemistry, archaeometry and natural sciences in archaeology, and outside the lab is active in several field projects in the eastern Mediterranean. Patrick is author of over 100 scientific papers in international journals, conference proceedings and books and is an A. von Humboldt Fellow and European Research Council Grantee.

"This is a book that consists of a collection of highly technical but practical chapters written by experts in the field. Given the rapidly advancing field of isotopic mass spectrometric analysis, it will be valuable as a reference guide for research workers and advanced students of these topics." ("Analytical and Bioanalytical Chemistry", 27 October 2012)

"This is a book that consists of a collection of highly technical but practical chapters written by experts in the field. Given the rapidly advancing field of isotopic mass spectrometric analysis, it will be valuable as a reference guide for research workers and advanced students of these topics." ( Analytical and Bioanalytical Chemistry , 27 October 2012)