Metallopharmaceuticals II
Diagnosis and Therapy
(Sprache: Englisch)
with contributions by numerous experts
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Produktdetails
Produktinformationen zu „Metallopharmaceuticals II “
with contributions by numerous experts
Klappentext zu „Metallopharmaceuticals II “
Biological inorganic chemistry is a field of research at the interface of inorganic and biological chemistry. The rapidly developing insights into the role of metals in biological systems has far-reaching implications not only for biological science but also for related disciplines, ranging from molecular medicine to the environment. In each volume the reader, whether engaged in chemistry, biochemistry, biology or molecular medicine, receives a comprehensive summary and critical overview of a topic of hight current interest written by leading international experts. Inorganic compounds offer much scope for the design of novel and therapeutic agents. The widespread use of paramagnetic metal complexes as effective contrast agents for magentic resonsance imaging (e.g. Gd) demonstrates that the toxicity of metals can be finely controlled via the approriate choice of ligands. The succcessful targeting of radioisotopes again depends on ligand design and metal oxidation state. Bismuth and gold complexes have long been used in medicine but only recently have advances been made in understanding the molecular basis of their mechanism of action. New areas with clinical potential include the use of polyoxometallates and fullerenes as antiviral agents and vanadium complexes as insulin mimetics.
Inhaltsverzeichnis zu „Metallopharmaceuticals II “
- Tweedle, M.F., Kumar, K.: Magnetic Resonance Imaging(MRI) Contrasting Agents- Packard, A.: Radiopharmaceuticals
- Rhule, J.T., Hill, C.L., Zheng, Z.: Polyoxometallates and Fullerenes as Anti-HIV Agents
- Orvig, C., Thompson, K.H.: Vanadium Insulin Mimetics
- Sunn, H., Sadler, P.J.: Bismuth Antiulcer Complexes
- Shaw, C.F.: Gold Anti-Arthritic Agents
Bibliographische Angaben
- 1999, 216 Seiten, Maße: 23,5 cm, Gebunden, Englisch
- Herausgegeben:Clarke, Michael J.; Sadler, Peter J.
- Verlag: Springer
- ISBN-10: 3540653082
- ISBN-13: 9783540653080
Sprache:
Englisch
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