Micro- and Nanoengineering of the Cell Surface

1 - Cell membrane engineering: an introduction
2 - Cell membrane biology
3 - Cell Surface Engineering by Chemical Reaction and Remodeling
4 - Noncovalent approaches
5 - liposome fusion
6 - fatty acid, GPI and cholesterol anchors
7 - Engineering the surface of cells using the biotin-avidin interaction
8 - Cell microencapsulation for tissue engineering and regenerative medicine
9 - glycosylphosphatidyl inositol (GPI), cholesterol anchors, palmitated protein A/G (hydrophobic), Protein painting/transfer, tethered ligands
10 - Recent advances in bioconjugation of living cells and their applications in metabolic oligosaccharide engineering.
11 -bio-orthogonal chemistry at cell surfaces
12 - Cell surface enzymatic engineering-based approaches to improve cell therapies
13 - Strategies for incorporation of biological cues into synthetic hydrogels
14 - Nanoparticle/cell interfacing, Control the stability of functioned (nano)materials on the cell surface: consideration and factors
15 - Study/imaging of cell surface engineering; tools for study cell-materials interface
16 - Cell surface/nanoparticle interfacing to manipulate cell fate
17 - Pushing the bacterial envelope: Genetic strategies for re-engineering bacterial surfaces with heterologous proteins and sugars
18 - Use of surface engineering for in vitro research tools and reagents
19 - Nucleic acids as nanoscale cellular patches
20 - Molecular Engineering of Cell and Tissue Surfaces with Polymer Thin Films
21 - Considerations for manufacturing surface modified cells for cell therapy applications, Challenges, regulatory, scale up, future

Assistant Professor, Department of Pharmaceutical Sciences, University of California, Irvine