Molecular Aspects of Cancer and its Therapy
(Sprache: Englisch)
This book highlights recent progress in the molecular, cellular and immunological mechanisms that contribute to the pathophysiology of cancer and the design of therapeutic modalities based upon these molecular insights. Areas of particular emphasis include...
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This book highlights recent progress in the molecular, cellular and immunological mechanisms that contribute to the pathophysiology of cancer and the design of therapeutic modalities based upon these molecular insights. Areas of particular emphasis include cancer immunology and the immunotherapy of cancer, the role of cytokines in modulating the social bahaviour of cancer cells, the genetic alterations that characterize human cancer and metastasis, and a consideration of the more experimental approaches to cancer therapy, including gene therapy using expression vectors for cytokines and their receptors, antisense RNA therapy, and anti-idiotypic antibody immunization. This volume serves to introduce the general reader as well as the cancer specialist to personalized perspectives of particular topics in cancer research by leading research groups in the field. The combination of a ''reviews''-approach with a more research-oriented approach in discussions of specific research topics provides a stimulating and, hopefully, forward-looking volume which serves to update selected aspects of cancer research today. This combination will be useful to both the beginner as well as the more advanced biomedical scientist.
Klappentext zu „Molecular Aspects of Cancer and its Therapy “
On the basis of the agreement signed between UNESCO and the Government of the Republic of Poland the International Institute for Cell and Molecular Biology of UNESCO was officially inaugurated in October 1995 in Warsaw, Poland, as part of the activity of the Global Network for Molecular and Cell Biology (MCBN) of UNESCO. The occasion was marked by the bringing together in Warsaw of a broad spectrum of cell and molecular biologists from around the world under the auspices of the Global MCBN UNESCO. At the conclusion of that week-long celebration it became clear that Polish cell and molecular biology had come of age in terms of its depth, vigor and impact on the global scene. At the suggestion of Professor Angelo Azzi, chairman of Global MCBN UNESCO, we considered the challenge of compiling a volume in the Molecular and Cell Biology Updates tMCBU) Series that would address the molecular basis of cancer and its therapy, but one that would additionally serve to highlight Polish contributions to this field of research. We accepted the challenge presented to us by Professor Azzi and are grateful to all contributors of the present volume for making this a pleasant and stimulating project. We requested each contributor to present his personal perspective of respective topics. As a consequence, we hope that each contribution has a distinctive individual flavor which reflects the role played by individual research groups in advancing science.
Inhaltsverzeichnis zu „Molecular Aspects of Cancer and its Therapy “
Genetic control of metastasis.- Cytokines in breast cancer cell dyshesion.- Clinical relevance of genetic alterations in lung cancer.- Recent advances in understanding function and mutations of breast cancer susceptibility genes.- Tumour immunology.- Cytokines in the host-tumor interaction.- Gene therapy of cancer.- Antisense strategy for cancer therapy.- Oligonucleotide therapeutics for human leukemia.- Genetic instability and tumor cell variation.
Bibliographische Angaben
- 2012, 1998., 238 Seiten, Kartoniert (TB), Englisch
- Herausgegeben von Mackiewicz, A.; Sehgal, P.B.
- Verlag: Springer
- ISBN-10: 3034898398
- ISBN-13: 9783034898393
Sprache:
Englisch
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