Natural Product Biosynthesis by Microorganisms and Plants

In vivo production of thiopeptide variants Microviridin biosynthesis Cyclotide isolation and characterization Ribosomally-encoded cyclic peptide toxins from mushrooms The Pictet-Spengler mechanism involved in the biosynthesis of tetrahydroisoquinoline antitumor antibiotics: novel function for a non-ribosomal peptide synthetase Discovery and biosynthesis of phosphonate and phosphinate natural products RlmN and AtsB as models for the overproduction and characterization of radical SAM proteins Fe(II)-dependent, uridine-5'-monophosphate a-ketoglutarate dioxygenases in the synthesis of 5'-modified nucleosides Heme-dependent Tailoring Enzymes in Natural Product Biosynthesis: Spectroscopic Characterisation of the L-tryptophan-nitrating Cytochrome P450 TxtE Oxidative Tailoring Reactions Catalysed by Non-heme Iron-dependent Enzymes: Streptorubin B Biosynthesis as an Example The rare fluorinated natural products and biotechnological prospects for fluorine enzymology Enzymatic chlorination and bromination Prenyltransferases of the dimethylallyltryptophan synthase superfamily Serine carboxypeptidase-like acyltransferases from plants 4-Methylideneimidazole-5-one-containing aminomutases in enediyne biosynthesis Tailoring enzymes acting on carrier protein-tethered substrates in natural product biosynthesis High-throughput colorimetric assays for nucleotide sugar formation and glycosyl transfer