Neuroimmunology

1. Immunology of the Neuromuscular Junction.- 1. Introduction.- 2. Structure of the Neuromuscular Junction.- 3. Antibodies to Presynaptic Element.- 4. Antibodies to Components of the Synaptic Cleft.- 5. Antibodies to the Acetylcholine Receptor.- 6. Antibodies to Subsynaptic Structures.- 7. Conclusion.- 8. References.- 2. Monoclonal Antibodies to Skeletal Muscle Cell Surface.- 1. Introduction.- 2. Regulation of Acetylcholine Receptors.- 3. Skeletal Muscle Acetylcholinesterases57.- 4. Monoclonal Antibodies.- 5. Discussion.- 6. References.- 3. Monoclonal Antibodies to Synaptic Contituents.- 1. Introduction.- 2. Preparation of Synaptic Junctions and Hybridoma Antibodies.- 3. Antibodies That Show Localized Binding in the Brain.- 4. Summary and Discussion.- 5. References.- 4. Analysis of Functional Cell Sets in the Immune System.- 1. T-Cell Sets.- 2. Functional Roles for Lyt Antigens.- 3. T-Cell Clones.- 4. References.- 5. Immunopathologic Disease of the Central Nervous System.- 1. Introduction.- 2. Immunopathologic Injury of the CNS: General Concepts.- 3. Blood Flow and the Traffic of Immunoglobulin and Lymphoid Cells in the CNS.- 4. Models Depicting Immunopathologically Mediated Injury of the CNS.- 5. Conclusion.- 6. References.- 6. The Use of Antibodies to Define and Study Major Cell Types in the Central and Peripheral Nervous System.- 1. Introduction.- 2. Development of Specific Marker Systems for Identifying the Major Cell Types in Nervous System Cultures.- 3. Monoclonal Antibodies.- 4. Applications.- 5. Conclusions.- 6. References.- 7. Immunological Studies of the Retina.- 1. Introduction.- 2. Production of Monoclonal Antibodies.- 3. Monoclonal Antibodies That Label Photoreceptors.- 4. Monoclonal Antibodies That Label Müller Cells.- 5. Discussion.- 6. References.- 8.Immunological Analysis of Cellular Heterogeneity in the Cerebellum.- 1. Introduction.- 2. Glial Markers.- 3. Neuronal Markers.- 4. Concluding Remarks.- 5. References.