Notch Signaling in Embryology and Cancer

Notch signaling in prevention ant therapy: fighting cancer with a two-sided sword.- Transcription factor RBPJ as a molecular switch in regulating the Notch response.- Unraveling of Hidden Secrets: The tumour suppressor Lethal (2) giant discs (Lgd)/CC2D1, Notch Signaling and Cancer.- Notch and endometrial cancer.- Notch and Esophageal Squamous Cell Carcinoma.- Notch signaling and liver cancer.- Notch inHead and Neck Cancer.- Notch Signaling and Human Papillomavirus-Associated Oral Tumorigenesis.- The impact of Notch signalingfor carcinogenesis and progression of non-melanoma skin cancer: lessons learned fromcancer stem cells, tumor angiogenesis, and beyond.- Notch Signaling in Thyroid Cancer.- The Relevance of Notch Signaling in Cancer Progression.- Notch Signaling and the Breast Cancer Microenvironment.- Notch pathway: a journey from notching phenotypes to cancer immunotherapy.- Index.

Jörg Reichrath is Professor for Dermatology and Deputy Director of the Clinic for Dermatology, Allergology and Venerology at the Saarland University Medical Center in Homburg, Germany. Reichrath has received his academic degrees (Dr. med.) from the Saarland University, Germany. His research interests include photobiology, dermato-endocrinology and dermato-oncology. He is a member of numerous national and international scientific organizations, including the German Dermatological Society (DDG), the Deutsche Krebsgesellschaft (DKG), the German Dermatologic Cooperative Oncology Group (DeCOG), the Arbeitsgemeinschaft Dermatologische Forschung (ADF) and the Deutsche Akademie für Photobiologie und Phototechnologie e. V. (DAFP). He has been awarded numerous prices including the Arnold-Rikli-price.



Sandra Reichrath is researcher and scientist at the Clinic for Dermatology, Allergology and Venerology at the Saarland University Medical Center Hospital in Homberg, Germany, where she at present works at the School of Health Professions. She received her academic degrees from the Faculty of Biology of the Albert-Ludwig-University, Freiburg, Germany. Her research interests include Notch signaling in glioblastoma and skin tumors.