Overcoming Steroid Insensitivity in Respiratory Disease
(Sprache: Englisch)
Written by well known experts in field, Overcoming Steroid Insensitivity in Respiratory Disease is the first book dedicated to dealing with the single most challenging management issue in long term steroid therapy.
Leider schon ausverkauft
versandkostenfrei
Buch (Gebunden)
75.65 €
37 DeutschlandCard Punkte
sammeln
- Lastschrift, Kreditkarte, Paypal, Rechnung
- Kostenlose Rücksendung
- Ratenzahlung möglich
Produktdetails
Produktinformationen zu „Overcoming Steroid Insensitivity in Respiratory Disease “
Written by well known experts in field, Overcoming Steroid Insensitivity in Respiratory Disease is the first book dedicated to dealing with the single most challenging management issue in long term steroid therapy.
Klappentext zu „Overcoming Steroid Insensitivity in Respiratory Disease “
Since their discovery in the 1950's, the therapeutic use of corticosteroids has been the mainstay of treatment for many chronic inflammatory diseases. Their utility has been tempered, however, by the increasing risk of side effects with higher dose therapy.In the treatment of airways diseases, side-effects can be limited by targeted delivery to the airway and lung, and significant progress has been made through the use of increasingly selective molecules, and through a variety of lung targeting strategies. Moreover, the recent developments in our understanding of the molecular and structural mechanisms of action of corticosteroid actions have suggested that it may be possible to develop new corticosteroids with intrinsically different pharmacology.
A combination of these developments will enable the design of agents with an enhanced therapeutic index and this book, aimed at specialists in pulmonology, provides the clinician who prescribes corticosteroid therapies with the most up-to-date information on one of the most significant therapeutic challenges to effective management of chronic inflammatory diseases.
* First book dedicated specifically to this major management issue for respiratory and general physicians.
* Authors well-known experts in field.
* Reviews important new advances in therapeutics.
Inhaltsverzeichnis zu „Overcoming Steroid Insensitivity in Respiratory Disease “
- Contents- List of contributors
- Preface
1 Molecular Mechanisms of Glucocorticoid Receptor Action
- Pankaj Bhavsar and Ian M. Adcock
2 Side Effects of Topical and Oral Glucocorticoids
- Heike Schäcke, Khusru Asadullah and Wolf-Dietrich Döcke
3 Glucocorticoid Receptor Subtypes and Steroid Sensitivity
- Robert H. Oakley and John A. Cidlowski
4 Dissociated Glucocorticoids
- Ian M. Adcock
5 Generalized Glucocorticoid Insensitivity: Clinical Phenotype and Molecular Mechanisms
- Evangelia Charmandari, Tomoshige Kino and George P. Chrousos
6 Corticosteroid Responsiveness in Asthma: Clinical Aspects
- Kian Fan Chung
7 Glucocorticoid-insensitive Asthma: Molecular Mechanisms
- John W. Bloom
8 Cigarette Smoke, Oxidative Stress and Corticosteroid Responsiveness
- Irfan Rahman and David Adenuga
9 Regulation of Glucocorticoid Sensitivity by Macrophage Migration Inhibitory Factor
- Eric F. Morand
10 Steroid-sparing Strategies: Long-acting Inhaled ²2 -Agonists
- Anna Miller-Larsson and Olof Selroos
11 Steroid-sparing Strategies: Other Combinations
- Gaetano Caramori, Kazuhiro Ito and Alberto Papi
12 Kinases as Anti-inflammatory Targets for Respiratory Disease
- Iain Kilty
13 Pharmacokinetic/Pharmacodynamic Factors and Steroid Sensitivity
- Gönther Hochhaus
14 Improved Lung Deposition: New Inhaler Devices
- Omar S. Usmani
- Index
Bibliographische Angaben
- 2008, 1. Auflage, 304 Seiten, Maße: 17,6 x 25,2 cm, Gebunden, Englisch
- Herausgegeben: Ian Adcock, Kian Fan Chung
- Verlag: Wiley & Sons
- ISBN-10: 0470058080
- ISBN-13: 9780470058084
- Erscheinungsdatum: 26.03.2008
Sprache:
Englisch
Kommentar zu "Overcoming Steroid Insensitivity in Respiratory Disease"
0 Gebrauchte Artikel zu „Overcoming Steroid Insensitivity in Respiratory Disease“
| Zustand | Preis | Porto | Zahlung | Verkäufer | Rating |
|---|
Schreiben Sie einen Kommentar zu "Overcoming Steroid Insensitivity in Respiratory Disease".
Kommentar verfassen