Pharmacology of Immunotherapeutic Drugs

Preface Chapter 1: Overview of the Immune System and its Pharmacological Targets.- Chapter 2: Modulation of the Innate Immune System.- Chapter 3: Modulation of the Adaptive Immune System.- Chapter 4: Respiratory Disorders of the Immune System and their Pharmacological Treatment.- Chapter 5: Inflammation of the Skin and its therapeutic topics.- Chapter 6: Inflammatory Diseases of the Gastrointestinal Tract and Pharmacological Treatments.- Chapter 7: Mechanisms of Autoimmunity and Pharmacologic Treatments.- Chapter 8: Transplantation: Immunologic Principles and Pharmacologic Agents.- Chapter 9: Immunopathogenesis, Immunization, and Treatment of Infectious Diseases.- Chapter 10: Cancer Immunotherapy.

Dr. Clinton Mathias received his Ph.D. in Biomedical Sciences with a concentration in Immunology from the University of Connecticut, where he studied the role of innate immune cells in the modulation of allergic asthma. His postdoctoral work at Boston Children's Hospital and Harvard Medical School focused on elucidating mechanisms regulating mast cell homeostasis and function in models of IgE-dependent asthma and food allergy. He is a founding faculty member of the Western New England University College of Pharmacy, where he teaches immunology, infectious diseases, and the pharmacology of immunotherapeutic drugs. His research interests are aimed at examining the genetic and environmental factors that govern mast cell responses during allergic inflammation.

Dr. Jeremy McAleer received his Ph.D. in Biomedical Science from the University of Connecticut where he studied the adjuvant effects of lipopolysaccharide on T cells. His postdoctoral work at Louisiana State University and the University of Pittsburgh focused on the regulation of pulmonary T cell immunity by commensal microbiota. In 2014, he joined the faculty at Marshall University School of Pharmacy in Huntington, WV, where he teaches immunology and pharmacology and conducts research on the regulation of T cell immunity by environmental factors.

Dr. Doreen Szollosi received her Ph.D. in Pathobiology from Brown University where she studied immunosuppression and lymphocyte apoptosis in a mouse model of polymicrobial sepsis at Rhode Island Hospital in Providence. She is a founding faculty member of the University of Saint Joseph School of Pharmacy in Hartford, CT where she enjoys teaching pharmacy students about the pharmacology of antimicrobials as well as drugs that affect the immune system. Her current research interests include studying the mechanisms of novel anti-inflammatory agents with dual pro-inflammatory cytokine and chemokine suppressive effects.