Prevention of Bone Metastases
(Sprache: Englisch)
Bone metastases continue to be a major cause of morbidity in cancer patients, but improved understanding of the biology of bone metastases has led to the identification of drugs that are of potential value in not only their treatment but also their...
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Klappentext zu „Prevention of Bone Metastases “
Bone metastases continue to be a major cause of morbidity in cancer patients, but improved understanding of the biology of bone metastases has led to the identification of drugs that are of potential value in not only their treatment but also their prevention. This book, written by recognized experts in the field, provides a detailed overview of current knowledge on this subject. One important focus of the book is the efficacy of bisphosphonates in preventing bone metastases in patients with breast, lung, and prostate cancer and disease progression in cases of multiple myeloma. The combined use of bisphosphonates and cytostatics is also discussed, with a report on first clinical data. Further topics addressed include the significance of the bone microenvironment, special issues in the elderly patient, the use of bone turnover markers, and initial findings obtained with denosumab.
Inhaltsverzeichnis zu „Prevention of Bone Metastases “
Rationale for the prevention of bone metastases: Preclinical models.- The role of bone microenvironment, vitamin D and calcium.- Bisphosphonates: Prevention of bone metastases in breast cancer.- Bisphosphonates: Prevention of bone metastases in lung cancer.- Bisphosphonates: Prevention of bone metastases in prostate cancer.- Bisphosphonates: Prevention of disease progression in patients with multiple myeloma.- Combination of bisphosphonates and cytostatics: Preclinical rationale and first clinical data.- Special issues in the elderly patient.- Denosumab: First data and ongoing studies on the prevention of bone metastases.- Special issues on the use of bone turnover markers.- Osteolytic and osteoblastic bone metastases: Two extremes of the same spectrum?
Bibliographische Angaben
- 2012, X, 234 Seiten, Maße: 16 x 24,1 cm, Gebunden, Englisch
- Herausgegeben: Markus Joerger, Michael Gnant
- Verlag: Springer, Berlin
- ISBN-10: 3642218911
- ISBN-13: 9783642218910
- Erscheinungsdatum: 05.01.2012
Sprache:
Englisch
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