Regulation of Organelle and Cell Compartment Signaling

244 Nuclear Receptor Coactivators

245 Corepressors in Mediating Repression by Nuclear Receptors

246 Steroid Hormone Receptor Signaling

247 Role of COUP-TFII in Congenital Diaphragmatic Hernia

248 Nuclear Receptors in Drosophila melanogaster

249 JAK-STAT Signaling

250 FOXO Transcription Factors: Key Targets of the PI3K-Akt Pathway

251 The Multi-gene Family of Transcription Factor AP-1

252 NF-KB: a Key Integrator of Cell Signaling

253 Transcriptional Regulation via the cAMP Responsive Activator CREB

254 The NFAT Family: Structure, Regulation and Biological Functions

255 Ubiquitination/Proteasome

256 The SMADs

257 Complexity of Stress Signaling

258 Signal Transduction in the Escherichia coli SOS Response

259 Oxidative Stress and Free Radical Signal Transduction

260 Screening Approaches to Identify Genes Required for DNA Double-Strand Break

261 Radiation Responses in Drosophila

262 Double-strand Break Recognition and its Repair by Non-homologous End Joining

263 ATM-Mediated Signaling Defends the Integrity of the Genome

264 Signaling to the p53 Tumor Suppressor through Pathways

265 The p53 Master Regulator and Rules of Engagement with Target Sequences

266 Nuclear and Cytoplasmic Functions of Abl Tyrosine Kinase

267 Radiation-induced Cytoplasmic Signaling

268 The Heat-Shock Response and the Stress of Misfolded Proteins

269 Hypoxia-Mediated Signaling Pathways

270 Regulation of mRNA Turnover by Cellular Stress

271 Oncogenic Stress Responses

272 Ubiquitin and FANC Stress Responses

273 Stress and g -H2AX

274 Translational Control by Amino Acids and Energy

275 Translation Control and Insulin Signaling

276 ER and oxidative stress: Implications in disease

Ralph A. Bradshaw is Professor Emeritus in the Department of Physiology and Biophysics at the University of California, Irvine. Prior to that he was on the faculty of the Department of Biological Chemistry, Washington University, and Professor and Chair of the Department of Biological Chemistry, University of California Irvine. He presently is Professor of Pharmacology at the University of California, San Diego. He served as president of FASEB, was the founding president of the Protein Society and was the treasurer of the ASBMB. He was the founding editor of Molecular and Cellular Proteomics. His research has focused on protein chemistry and proteomics, with emphasis on the structure and function of growth factors and their receptors, particularly nerve growth factor and ?broblast growth factor, and the involvement of receptor tyrosine kinases in cell signaling. He has also studied the role of proteolytic processing and N-terminal modi?cation in protein stability and turnover. Edward A. Dennis is Distinguished Professor and former Chair of the Department of Chemistry and Biochemistry and Professor in the Department of Pharmacology in the School of Medicine at the University of California, San Diego. He is also Editor-in-Chief of the Journal of Lipid Research.

"In order to keep researchers and students up to date on developments in the field, 55 articles were selected and reprinted from the 2008 second edition of the 'Handbook of Cell Signaling' on the transcriptional regulation and the function of nuclei and other subcellular organelles in signaling activities. After an overview, they cover nuclear signaling in transcription, chromatic remodeling, and stress response; signaling to and from intracellular compartments; and cell cycle and cell death signaling. This is one of four volumes of such reprints, called the Cell Signaling Collection."--Reference and Research Book News

"In order to keep researchers and students up to date on developments in the field, 55 articles were selected and reprinted from the 2008 second edition of the 'Handbook of Cell Signaling' on the transcriptional regulation and the function of nuclei and other subcellular organelles in signaling activities. After an overview, they cover nuclear signaling in transcription, chromatic remodeling, and stress response; signaling to and from intracellular compartments; and cell cycle and cell death signaling. This is one of four volumes of such reprints, called the Cell Signaling Collection."--Reference and Research Book News