Reproductive and Developmental Toxicology

Foreword

Section-I: General

Section-II: Safety Evaluation and Toxicity Testing Models

Section-III: Nanoparticles and Radiation

Section-IV: Gases and Solvents

Section-V: Smoking, Alcohol, and Drugs of Abuse and Addiction

Section-VI: Food Additives, Nutraceuticals, and Pharmaceuticals

Section-VII: Metals

Section-VIII: Pesticides and Other Environmental Contaminants

Section-IX: Phytotoxicants

Section-X: Biotoxins

Section-XI: Special Topics

Section-XII: Endocrine Disruption, Mutagenicity, Carcinogenicity, Infertility and Teratogenicity

Section-XIII: Toxicologic Pathology

Section-XIV: Placental Toxicity

Section-XV: Domestic, Wildlife and Aquatic Species

Dr. Ramesh C. Gupta, Professor & Head of Toxicology Department at Murray State university, is engaged in experimental brain research in relation to Alzheimer's disease (AD) and pesticide toxicity. He has delivered lectures in Australia, Italy, Japan, Germany, France, Switzerland, Spain, Czech Republic, China, South Korea, and Sweden. He served the panels of NIH, CDC, NIOSH, and NAS. He has 350 publications to his credit, including seven major books with Elsevier: (1) Toxicology of Organophosphate and Carbamate Compounds, (2) Veterinary Toxicology: Basic and Clinical Principles, (3) Handbook of Toxicology of Chemical Warfare Agents, (4) Anticholinesterase Pesticides: Metabolism, Neurotoxicity, and Epidemiology, (5) Reproductive and Developmental Toxicology, (6) Biomarkers in Toxicology and (7) Neutraceuticals. He is recipient of Murray State University's distinguished researcher award of the year-2006. He is a diplomate of American Board of Toxicology, and fellow of American College of Toxicology, American College of Nutrition, and Academy of Toxicological Sciences.

"Overall, this book will be very useful as an authoritative source of critically analyzed information for anybody seeking insight into reproductive and developmental physiology and its perturbation by a vast array of endogenous and environmental factors."--Frank Welsch, D.V.M., Ph.D., D.A.B.T., Principal Scientist, Orbitox International Toxicology Consultants "Reproductive and Developmental Toxicology provides comprehensive coverage of historical and current knowledge in this specialized field of toxicology. It comprises 86 chapters approaches and model systems are described by experts in the field. Several subsequent sections provide historical and current information on a number of developmental toxicants, including nanoparticles and radiation; gases and solvents; smoking, alcohol, and drugs of addiction; food additives, metals, and pesticides; and phytotoxins and biotoxins. Each chapter is well organized, with an introduction, a full description of the characteristics, mechanisms where known, effects of each toxicant, and concluding remarks and future directions. Figures are used effectively and strategically to illustrate a number of topics. The contributors to Reproductive and Developmental Toxicology are an international group of almost 180 scientists, who represent academic institutions, pharmaceutical industries, and governmental agencies. They provide an exceptional breadth of expertise in the wide range of topics covered in this extensive volume. This book will be most useful to the scientifically trained reader seeking a detailed understanding of the experimental background and currently studied topics of reproductive and developmental toxicology."--Veterinary Pathology Online "The 15 sections in the book comprehensively cover a wide range of crucial aspects of developmental and reproductive toxicology as relates to experimental models commonly used in pharmaceutical, agro-chemical and environmental toxicology research. Excellent examples of normal and

"Overall, this book will be very useful as an authoritative source of critically analyzed information for anybody seeking insight into reproductive and developmental physiology and its perturbation by a vast array of endogenous and environmental factors."-- Frank Welsch, D.V.M., Ph.D., D.A.B.T., Principal Scientist, Orbitox International Toxicology Consultants

" Reproductive and Developmental Toxicology provides comprehensive coverage of historical and current knowledge in this specialized field of toxicology. It comprises 86 chapters approaches and model systems are described by experts in the field. Several subsequent sections provide historical and current information on a number of developmental toxicants, including nanoparticles and radiation; gases and solvents; smoking, alcohol, and drugs of addiction; food additives, metals, and pesticides; and phytotoxins and biotoxins. Each chapter is well organized, with an introduction, a full description of the characteristics, mechanisms where known, effects of each toxicant, and concluding remarks and future directions. Figures are used effectively and strategically to illustrate a number of topics.. The contributors to Reproductive and Developmental Toxicology are an international group of almost 180 scientists, who represent academic institutions, pharmaceutical industries, and governmental agencies. They provide an exceptional breadth of expertise in the wide range of topics covered in this extensive volume. This book will be most useful to the scientifically trained reader seeking a detailed understanding of the experimental background and currently studied topics of reproductive and developmental toxicology."-- Veterinary Pathology Online

"The 15 sections in the book comprehensively cover a wide range of crucial aspects of developmental and reproductive toxicology as relates to experimental models commonly used in pharmaceutical, agro-chemical and environmental toxicology research. Excellent examples of