Shock, Sepsis, and Organ Failure

Gut as a Source of Organ Failure.- Hypoxic Damage of the Gut in Shock.- Discussion.- Experimental Evidence of Bacterial Translocation in Trauma.- Discussion.- Bacterial Translocation in a Baboon Model of Hypovolemic-Traumatic Shock.- Discussion.- Bacterial Translocation Across a Histologically Intact Intestinal Mucosa.- Discussion.- Clinical Evidence of Bacterial Translocation from the Gut.- Discussion.- Role of Bacterial Translocation and Selective Gut Decontamination in the Development of Multiple Organ Failure.- Discussion.- Metabolic Aspects of the Liver in Sepsis.- The Liver as Modulator of the Host-Defense Response: Host-Defense Failure Disease as a Manifestation of Hepatic Decompensation.- Discussion.- Concepts of Liver Protein Metabolism in Sepsis.- Discussion.- Increased Glucose Uptake and Superoxide Anion Production After Priming of Activation of Hepatic Phagocytes: A Potential Source of Liver Damage.- Discussion.- Modulation of Hepatic Function in Endotoxemia by Intercellular Communication.- Discussion.- Endothelium as a Target in Sepsis.- Cytokine-Dependent Interleukin-8 Expression and its Role in Cell Communication.- Discussion.- Trauma and Sepsis Induced Activation of Granulocytes, Monocytes/Macrophages and Endothelial Cells in Primates.- Discussion.- Molecular Mechanisms of Neutrophil-Mediated Pulmonary Microvascular Injury: Role of Adhesion Proteins.- Discussion.- Pathogenetic Linkages Between Gram Negative Septic Shock and the Cellular Initiation and Regulation of Coagulation.- Discussion.- Sepsis, Disseminated Intravascular Coagulation and Multiorgan Failure: Catastrophic Events in Severe Burns.- Discussion.- Mechanisms of Vascular Impairment During Endotoxaemia with Special Reference to the Role of the L-arginine Pathway.- Discussion.- Permeability Changes During Experimental Endotoxemia and Sepsis.- Discussion.- Final Discussion.