Singer & Monaghan's Cervical and Lower Genital Tract Precancer

Preface to the Third Edition, ix
 
Preface to the First Edition, x
 
Acknowledgements, xi
 
1 The Histopathology of Lower Genital Tract Neoplasia, 1
 
1.1 Introduction, 1
 
1.2 Terminology, 1
 
1.3 Histopathologic features of cervical intraepithelial neoplasia or squamous intraepithelial lesion, 3
 
1.4 Cervical glandular intraepithelial neoplasia and adenocarcinoma in situ, 6
 
1.5 Early invasive carcinoma, 7
 
1.6 Vaginal intraepithelial neoplasia, 11
 
1.7 Vulval precancer, 11
 
1.8 Related topics, 12
 
1.9 Further reading, 13
 
2 Human Papillomaviruses in the Pathogenesis of Lower Genital Tract Neoplasia, 14
 
2.1 Introduction, 14
 
2.2 Characteristics of human papillomaviruses, 14
 
2.3 Manifestations of genital human papillomavirus infections, 15
 
2.4 Prevalence of genital human papillomavirus infections, 18
 
2.5 Transmission of genital human papillomavirus infections, 19
 
2.6 Risk factors for genital human papillomavirus infections, 19
 
2.7 Natural history of cervical human papillomavirus infections, 19
 
2.8 Molecular pathways of human papillomavirus oncogenesis, 19
 
2.9 The effect of human papillomavirus/host cell interaction: a prerequisite for neoplasia, 21
 
2.10 The role of oncogenic human papillomavirus detection in the prevention of lower genital tract precancer, 22
 
2.11 Further reading, 23
 
3 Examination for Cervical Precancer: Use of colposcopy, 24
 
3.1 Introduction, 24
 
3.2 Tissue basis for colposcopy, 24
 
3.3 The colposcopic examination, 25
 
3.4 Video colposcopy, 31
 
3.5 Image and electronic data management, 31
 
3.6 Further reading, 32
 
4 Colposcopy of the Normal Cervix: A prerequisite to establishing the diagnosis of cervical precancer, 33
 
4.1 Introduction, 33
 
4.2 Cervical epithelium: natural