Skin Pharmacology and Toxicology

Dermatological Drug Development - A Review of some Important Issues.- Carbohydrate, Protein and Lipid Metabolism in the Skin; Biochemical and Molecular Aspects.- Hormone Receptors in the Skin.- Skin Permeability and Models of Percutaneous Absorption.- Skin as a Portal of Entry for Systemic Effect: Xenobiotic Metabolism85 D.R. Bickers.- Animal Models Used in Cutaneous Pharmacology.- Hyperplastic Transformation: the Response of the Skin to Irritation and Injury.- The Evaluation of Cutaneous Toxicity: Past and Future.- In Vitro Biochemical Markers of Skin Toxicity.- The Use of Cultured Human Keratinocytes as a Model System for Skin Pharmacology and Toxicology.- Pro-Inflammatory Mediators and Human Skin Disease.- Studies of Photoaging.- Photosensitization Chemically Induced: Mechanisms and Clinical Aspects.- Molecular and Cellular Mechanisms of Multistage Carcinogenesis; Role of Oncogenes and Intercellular Communication.- Contact and Atopic Dermatitis.- In Vitro Expanded Human Keratinocytes: Clinical and Biological Experiences.- A Comparative Evaluation of Sun Protective Properties of a Shea Butter by Reflectance Spectroscopy, Laser Doppler Flowmetry and Visual Scoring.- A Computer System for Contact Dermatitis.- Nuclear Aberrations in Anagen Hair Follicle Cells; a Novel in Vivo Assay for the Detection of Genotoxic Agents.- A New Evaluation Method of Skin Plastoelasticity.- An Interspecies Comparison of Skin Structure (Hair Follicle Area as Determined by a Novel Technique) and Skin Permeability.- Chemical-Induced Differentiation of Cultured Human Keratinocytes as Measured by Cell Size Distribution.- Contributors.