Small Molecule - Protein Interactions
(Sprache: Englisch)
Based on the international workshop on 'Small Molecule - Protein Interactions' held in Berlin, April 24-26, 2002, researchers from industry and academic laboratories describe novel and efficient ways selecting promising new drug targets and developing small...
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Based on the international workshop on 'Small Molecule - Protein Interactions' held in Berlin, April 24-26, 2002, researchers from industry and academic laboratories describe novel and efficient ways selecting promising new drug targets and developing small molecule inhibitors against them. The structure of the book corresponds to the different aspects of the drug discovery process. All chapters are written by leading experts in the field, who present and discuss the most recent state-of-the-art tools and techniques for the development of novel drugs. The value of the book lies in surveying and summarizing the approaches taken by different companies and institutions giving the reader a balanced view on the use of the latest techniques on the one hand and experience-based assistance in selecting appropriate tools for their own work on the other hand.
Inhaltsverzeichnis zu „Small Molecule - Protein Interactions “
1. Drug Discovery Opportunities2. Target Analysis: A Priori Assessment of Druggability
3. Drug Discovery at Signaling Interfaces
4. Chemical Genomics of Orphan Nuclear Receptors
5. High-Throughput X-Ray Techniques and Drug Discovery
6. NMR in Medicinal Chemistry
7. Creating Knowledge from High-Throughput Screening Data
8. From Structure to Recognition Principles: Mining in Crystal Data as a Prerequisite for Drug Design
9. Practical Database Screening with Docking Tools
10. De Novo Design Methods
11. From Protein Domains to Drug Candidates - Natural Products as Guiding Principles in Compound Library Design and Synthesis
12. Discovery of New MCRs, Chemical Evolution and Lead Optimization
13. The Impact of Combinatorial Chemistry on Drug Discovery
- Previous Volumes Published in This Series
Bibliographische Angaben
- 2003, 228 Seiten, mit farbigen Abbildungen, Maße: 22,3 cm, Gebunden, Englisch
- Ed. by H. Waldmann and M. Koppitz
- Verlag: Springer
- ISBN-10: 3540439846
- ISBN-13: 9783540439844
Sprache:
Englisch
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